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Early Gastric Cancer: Update on Prevention, Diagnosis and Treatment

Author

Listed:
  • Clara Benedetta Conti

    (Interventional Endoscopy, Foundation IRCCS San Gerardo dei Tintori, 20900 Monza, Italy)

  • Stefano Agnesi

    (Department of Surgery and Translational Medicine, Foundation IRCCS San Gerardo dei Tintori, University of Milano-Bicocca, 20900 Monza, Italy)

  • Miki Scaravaglio

    (Interventional Endoscopy, Foundation IRCCS San Gerardo dei Tintori, 20900 Monza, Italy)

  • Pietro Masseria

    (Department of Surgery and Translational Medicine, Foundation IRCCS San Gerardo dei Tintori, University of Milano-Bicocca, 20900 Monza, Italy)

  • Marco Emilio Dinelli

    (Interventional Endoscopy, Foundation IRCCS San Gerardo dei Tintori, 20900 Monza, Italy)

  • Massimo Oldani

    (General Surgery Unit, Foundation IRCCS San Gerardo dei Tintori, 20900 Monza, Italy)

  • Fabio Uggeri

    (Department of Surgery and Translational Medicine, Foundation IRCCS San Gerardo dei Tintori, University of Milano-Bicocca, 20900 Monza, Italy)

Abstract

Gastric cancer (GC) is a relevant public health issue as its incidence and mortality rates are growing worldwide. There are recognized carcinogen agents, such as obesity, tobacco, meat, alcohol consumption and some dietary protective factors. Strategies of early diagnosis through population-based surveillance programs have been demonstrated to be effective in lowering the morbidity and mortality related to GC in some countries. Indeed, the detection of early lesions is very important in order to offer minimally invasive treatments. Endoscopic resection is the gold standard for lesions with a low risk of lymph node metastasis, whereas surgical mini-invasive approaches can be considered in early lesions when endoscopy is not curative. This review outlines the role of lifestyle and prevention strategies for GC, in order to reduce the patients’ risk factors, implement the surveillance of precancerous conditions and, therefore, improve the diagnosis of early lesions. Furthermore, we summarize the available treatments for early gastric cancer.

Suggested Citation

  • Clara Benedetta Conti & Stefano Agnesi & Miki Scaravaglio & Pietro Masseria & Marco Emilio Dinelli & Massimo Oldani & Fabio Uggeri, 2023. "Early Gastric Cancer: Update on Prevention, Diagnosis and Treatment," IJERPH, MDPI, vol. 20(3), pages 1-21, January.
  • Handle: RePEc:gam:jijerp:v:20:y:2023:i:3:p:2149-:d:1046143
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    References listed on IDEAS

    as
    1. Kui Son Choi & Jae Kwan Jun & Eun-Cheol Park & Sohee Park & Kyu Won Jung & Mi Ah Han & Il Ju Choi & Hoo-Yeon Lee, 2012. "Performance of Different Gastric Cancer Screening Methods in Korea: A Population-Based Study," PLOS ONE, Public Library of Science, vol. 7(11), pages 1-8, November.
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