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Comprehensive Study of a Diabetes Mellitus Mathematical Model Using Numerical Methods with Stability and Parametric Analysis

Author

Listed:
  • Mohammad AlShurbaji

    (Biomedical Engineering Graduate Program, American University of Sharjah, Sharjah P.O. Box 26666, United Arab Emirates)

  • Lamis Abdul Kader

    (Biomedical Engineering Graduate Program, American University of Sharjah, Sharjah P.O. Box 26666, United Arab Emirates)

  • Hadia Hannan

    (Biomedical Engineering Graduate Program, American University of Sharjah, Sharjah P.O. Box 26666, United Arab Emirates)

  • Maruf Mortula

    (Department of Civil Engineering, American University of Sharjah, Sharjah P.O. Box 26666, United Arab Emirates)

  • Ghaleb A. Husseini

    (Department of Chemical and Biological Engineering, American University of Sharjah, Sharjah P.O. Box 26666, United Arab Emirates
    Material Science and Engineering PhD Program, College of Arts and Sciences, American University of Sharjah, Sharjah P.O. Box 26666, United Arab Emirates)

Abstract

Diabetes is sweeping the world as a silent epidemic, posing a growing threat to public health. Modeling diabetes is an effective method to monitor the increasing prevalence of diabetes and develop cost-effective strategies that control the incidence of diabetes and its complications. This paper focuses on a mathematical model known as the diabetes complication (DC) model. The DC model is analyzed using different numerical methods to monitor the diabetic population over time. This is by analyzing the model using five different numerical methods. Furthermore, the effect of the time step size and the various parameters affecting the diabetic situation is examined. The DC model is dependent on some parameters whose values play a vital role in the convergence of the model. Thus, parametric analysis was implemented and later discussed in this paper. Essentially, the Runge–Kutta (RK) method provides the highest accuracy. Moreover, Adam–Moulton’s method also provides good results. Ultimately, a comprehensive understanding of the development of diabetes complications after diagnosis is provided in this paper. The results can be used to understand how to improve the overall public health of a country, as governments ought to develop effective strategic initiatives for the screening and treatment of diabetes.

Suggested Citation

  • Mohammad AlShurbaji & Lamis Abdul Kader & Hadia Hannan & Maruf Mortula & Ghaleb A. Husseini, 2023. "Comprehensive Study of a Diabetes Mellitus Mathematical Model Using Numerical Methods with Stability and Parametric Analysis," IJERPH, MDPI, vol. 20(2), pages 1-23, January.
  • Handle: RePEc:gam:jijerp:v:20:y:2023:i:2:p:939-:d:1025169
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    References listed on IDEAS

    as
    1. Abdelfatah Kouidere & Abderrahim Labzai & Hanane Ferjouchia & Omar Balatif & Mostafa Rachik, 2020. "A New Mathematical Modeling with Optimal Control Strategy for the Dynamics of Population of Diabetics and Its Complications with Effect of Behavioral Factors," Journal of Applied Mathematics, Hindawi, vol. 2020, pages 1-12, June.
    2. Hannah Al Ali & Alireza Daneshkhah & Abdesslam Boutayeb & Zindoga Mukandavire, 2022. "Examining Type 1 Diabetes Mathematical Models Using Experimental Data," IJERPH, MDPI, vol. 19(2), pages 1-20, January.
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    Cited by:

    1. Farman, Muhammad & Ahmad, Aqeel & Zehra, Anum & Nisar, Kottakkaran Sooppy & Hincal, Evren & Akgul, Ali, 2024. "Analysis and controllability of diabetes model for experimental data by using fractional operator," Mathematics and Computers in Simulation (MATCOM), Elsevier, vol. 218(C), pages 133-148.

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