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Presence of Depression Is Associated with Functional Impairment in Middle-Aged and Elderly Chinese Adults with Vascular Disease/Diabetes Mellitus—A Cross-Sectional Study

Author

Listed:
  • Yuxiao Zhao

    (Key Laboratory of Cognition and Personality, Faculty of Psychology, Ministry of Education, Southwest University, Chongqing 400715, China
    These authors contributed equally to this work.)

  • Yueying Zhang

    (Key Laboratory of Cognition and Personality, Faculty of Psychology, Ministry of Education, Southwest University, Chongqing 400715, China
    These authors contributed equally to this work.)

  • Kayla M. Teopiz

    (Mood Disorders Psychopharmacology Unit, Toronto, ON M5T 2S8, Canada)

  • Leanna M. W. Lui

    (Mood Disorders Psychopharmacology Unit, Toronto, ON M5T 2S8, Canada)

  • Roger S. McIntyre

    (Mood Disorders Psychopharmacology Unit, Toronto, ON M5T 2S8, Canada
    Department of Psychiatry, University of Toronto, Toronto, ON M5T 1R8, Canada
    Department of Pharmacology, University of Toronto, Toronto, ON M5S 1A8, Canada)

  • Bing Cao

    (Key Laboratory of Cognition and Personality, Faculty of Psychology, Ministry of Education, Southwest University, Chongqing 400715, China
    National Demonstration Center for Experimental Psychology Education, Southwest University, Chongqing 400715, China)

Abstract

Objectives: The association between chronic diseases and depression has received increasing attention, and are both considered to increase the risk of functional impairment. However, previous research evidence is controversial. Our study aimed to investigate the association between depression, three types of vascular disease (i.e., hypertension, myocardial infarction, stroke), diabetes mellitus, and functional impairment in middle-aged and elderly Chinese people. Methods: We designed a cross sectional study. Data were collected from the China Health and Retirement Longitudinal Study (CHARLS) in 2018. Logistic regression models were used to explore the association between independent variables and functional status. Results: Lower functional status was significantly associated with comorbid depression and vascular disease/diabetes mellitus (Activity of Daily Living/Instrumental Activity of Daily Living: Adjusted OR of Hypertension, Diabetes mellitus, Myocardial infarction, Stroke is 3.86/4.30, 3.80/4.38, 3.60/4.14, 6.62/7.72, respectively; all p < 0.001). Conclusions: Depression is associated with functional decline in middle-aged and elderly Chinese individuals with vascular disease/diabetes mellitus. Identifying mediational factors and preventative strategies to reduce concurrent depression in persons with vascular diseases should be a priority therapeutic vista.

Suggested Citation

  • Yuxiao Zhao & Yueying Zhang & Kayla M. Teopiz & Leanna M. W. Lui & Roger S. McIntyre & Bing Cao, 2023. "Presence of Depression Is Associated with Functional Impairment in Middle-Aged and Elderly Chinese Adults with Vascular Disease/Diabetes Mellitus—A Cross-Sectional Study," IJERPH, MDPI, vol. 20(2), pages 1-11, January.
    • Handle: RePEc:gam:jijerp:v:20:y:2023:i:2:p:1602-:d:1037156
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    References listed on IDEAS

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    1. Septi Kurnia Lestari & Nawi Ng & Paul Kowal & Ailiana Santosa, 2019. "Diversity in the Factors Associated with ADL-Related Disability among Older People in Six Middle-Income Countries: A Cross-Country Comparison," IJERPH, MDPI, vol. 16(8), pages 1-12, April.
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