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Projecting Lifetime Health Outcomes and Costs Associated with the Ambient Fine Particulate Matter Exposure among Adult Women in Korea

Author

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  • Gyeyoung Choi

    (College of Pharmacy, Ewha Womans University, Seoul 03760, Korea)

  • Yujeong Kim

    (College of Pharmacy, Ewha Womans University, Seoul 03760, Korea
    Korean Health Insurance Review & Assessment Service, Wonju 26465, Korea)

  • Gyeongseon Shin

    (College of Pharmacy, Ewha Womans University, Seoul 03760, Korea)

  • SeungJin Bae

    (College of Pharmacy, Ewha Womans University, Seoul 03760, Korea)

Abstract

We sought to estimate the lifetime healthcare costs and outcomes associated with the exposure to the escalated concentration of fine particulate matter (particle size < 2.5 μm, PM 2.5 ) among adult Korean women. We adapted a previously developed Markov model, and a hypothetical cohort composed of Korean women was exposed to either a standard (15 μg/m 3 ) or increased (25 μg/m 3 ) concentration of PM 2.5 . The time horizon of the analysis was 60 years, and the cycle length was 1 year. The outcomes were presented as direct healthcare costs and quality-adjusted life years (QALYs), and costs were discounted annually at 5%. Deterministic and probabilistic sensitivity analyses were performed. The model estimated that when the exposure concentration was increased by 10 μg/m 3 , the lifetime healthcare cost increased by USD 9309, which is an 11.3% increase compared to the standard concentration group. Women exposed to a higher concentration of PM 2.5 were predicted to live 30.64 QALYs, compared to 32.08 QALYs for women who were exposed to the standard concentration of PM 2.5 . The tendency of a higher cost and shorter QALYs at increased exposure was consistent across a broad range of sensitivity analyses. The negative impact of PM 2.5 was higher on cost than on QALYs and accelerated as the exposure time increased, emphasizing the importance of early intervention.

Suggested Citation

  • Gyeyoung Choi & Yujeong Kim & Gyeongseon Shin & SeungJin Bae, 2022. "Projecting Lifetime Health Outcomes and Costs Associated with the Ambient Fine Particulate Matter Exposure among Adult Women in Korea," IJERPH, MDPI, vol. 19(5), pages 1-14, February.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:5:p:2494-:d:755137
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    References listed on IDEAS

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    1. SeungJin Bae & SooOk Lee & Eun Bae & Sunmee Jang, 2013. "Korean Guidelines for Pharmacoeconomic Evaluation (Second and Updated Version)," PharmacoEconomics, Springer, vol. 31(4), pages 257-267, April.
    2. Frank A. Sonnenberg & J. Robert Beck, 1993. "Markov Models in Medical Decision Making," Medical Decision Making, , vol. 13(4), pages 322-338, December.
    3. Suganthi Jaganathan & Lindsay M. Jaacks & Melina Magsumbol & Gagandeep K. Walia & Nancy L. Sieber & Roopa Shivasankar & Preet K. Dhillon & Safraj Shahul Hameed & Joel Schwartz & Dorairaj Prabhakaran, 2019. "Association of Long-Term Exposure to Fine Particulate Matter and Cardio-Metabolic Diseases in Low- and Middle-Income Countries: A Systematic Review," IJERPH, MDPI, vol. 16(14), pages 1-18, July.
    4. Simone Ohlwein & Ron Kappeler & Meltem Kutlar Joss & Nino Künzli & Barbara Hoffmann, 2019. "Health effects of ultrafine particles: a systematic literature review update of epidemiological evidence," International Journal of Public Health, Springer;Swiss School of Public Health (SSPH+), vol. 64(4), pages 547-559, May.
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