IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v19y2022i4p2395-d753263.html
   My bibliography  Save this article

MiRNA: Biological Regulator in Host-Parasite Interaction during Malaria Infection

Author

Listed:
  • Poonam Kataria

    (Parasite-Host Biology, National Institute of Malaria Research, Dwarka, New Delhi 110077, India)

  • Neha Surela

    (Parasite-Host Biology, National Institute of Malaria Research, Dwarka, New Delhi 110077, India)

  • Amrendra Chaudhary

    (Parasite-Host Biology, National Institute of Malaria Research, Dwarka, New Delhi 110077, India)

  • Jyoti Das

    (Parasite-Host Biology, National Institute of Malaria Research, Dwarka, New Delhi 110077, India
    Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India)

Abstract

Malaria is a severe life-threatening disease caused by the bites of parasite-infected female Anopheles mosquitoes. It remains a significant problem for the most vulnerable children and women. Recent research has helped establish the relationship between microRNAs (miRNAs) and many other diseases. MiRNAs are the class of small non-coding RNAs consisting of 18–23 nucleotides in length that are evolutionarily conserved and regulate gene expression at a post-transcriptional level and play a significant role in various molecular mechanisms such as cell survival, cell proliferation, and differentiation. MiRNAs can help detect malaria infection as the malaria parasite could alter the miRNA expression of the host. These alterations can be diagnosed by the molecular diagnostic tool that can indicate disease. We summarize the current understanding of miRNA during malaria infection. miRNAs can also be used as biomarkers, and initial research has unearthed their potential in diagnosing and managing various diseases such as malaria.

Suggested Citation

  • Poonam Kataria & Neha Surela & Amrendra Chaudhary & Jyoti Das, 2022. "MiRNA: Biological Regulator in Host-Parasite Interaction during Malaria Infection," IJERPH, MDPI, vol. 19(4), pages 1-11, February.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:4:p:2395-:d:753263
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/19/4/2395/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/19/4/2395/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Jun Lu & Gad Getz & Eric A. Miska & Ezequiel Alvarez-Saavedra & Justin Lamb & David Peck & Alejandro Sweet-Cordero & Benjamin L. Ebert & Raymond H. Mak & Adolfo A. Ferrando & James R. Downing & Tyler , 2005. "MicroRNA expression profiles classify human cancers," Nature, Nature, vol. 435(7043), pages 834-838, June.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Shubin W Shahab & Lilya V Matyunina & Roman Mezencev & L DeEtte Walker & Nathan J Bowen & Benedict B Benigno & John F McDonald, 2011. "Evidence for the Complexity of MicroRNA-Mediated Regulation in Ovarian Cancer: A Systems Approach," PLOS ONE, Public Library of Science, vol. 6(7), pages 1-12, July.
    2. Roy Navon & Hui Wang & Israel Steinfeld & Anya Tsalenko & Amir Ben-Dor & Zohar Yakhini, 2009. "Novel Rank-Based Statistical Methods Reveal MicroRNAs with Differential Expression in Multiple Cancer Types," PLOS ONE, Public Library of Science, vol. 4(11), pages 1-10, November.
    3. Ander Muniategui & Rubén Nogales-Cadenas & Miguél Vázquez & Xabier L. Aranguren & Xabier Agirre & Aernout Luttun & Felipe Prosper & Alberto Pascual-Montano & Angel Rubio, 2012. "Quantification of miRNA-mRNA Interactions," PLOS ONE, Public Library of Science, vol. 7(2), pages 1-10, February.
    4. Rao Youlan & Lee Yoonkyung & Jarjoura David & Ruppert Amy S & Liu Chang-gong & Hsu Jason C & Hagan John P, 2008. "A Comparison of Normalization Techniques for MicroRNA Microarray Data," Statistical Applications in Genetics and Molecular Biology, De Gruyter, vol. 7(1), pages 1-20, July.
    5. Ping Xuan & Ke Han & Maozu Guo & Yahong Guo & Jinbao Li & Jian Ding & Yong Liu & Qiguo Dai & Jin Li & Zhixia Teng & Yufei Huang, 2013. "Prediction of microRNAs Associated with Human Diseases Based on Weighted k Most Similar Neighbors," PLOS ONE, Public Library of Science, vol. 8(8), pages 1-15, August.
    6. Wei Meng & Joseph P McElroy & Stefano Volinia & Jeff Palatini & Sarah Warner & Leona W Ayers & Kamalakannan Palanichamy & Arnab Chakravarti & Tim Lautenschlaeger, 2013. "Comparison of MicroRNA Deep Sequencing of Matched Formalin-Fixed Paraffin-Embedded and Fresh Frozen Cancer Tissues," PLOS ONE, Public Library of Science, vol. 8(5), pages 1-9, May.
    7. Ming-yang Song & Kai-feng Pan & Hui-juan Su & Lian Zhang & Jun-ling Ma & Ji-you Li & Yasuhito Yuasa & Daehee Kang & Yong Sung Kim & Wei-cheng You, 2012. "Identification of Serum MicroRNAs as Novel Non-Invasive Biomarkers for Early Detection of Gastric Cancer," PLOS ONE, Public Library of Science, vol. 7(3), pages 1-9, March.
    8. Julia E. Rager & Rebecca C. Fry, 2012. "The Aryl Hydrocarbon Receptor Pathway: A Key Component of the microRNA-Mediated AML Signalisome," IJERPH, MDPI, vol. 9(5), pages 1-15, May.
    9. Ya-Hui Huang & Kwang-Huei Lin & Hua-Chien Chen & Ming-Ling Chang & Chao-Wei Hsu & Ming-Wei Lai & Tse-Ching Chen & Wei-Chen Lee & Yi-Hsin Tseng & Chau-Ting Yeh, 2012. "Identification of Postoperative Prognostic MicroRNA Predictors in Hepatocellular Carcinoma," PLOS ONE, Public Library of Science, vol. 7(5), pages 1-10, May.
    10. Yun Xiao & Chaohan Xu & Jinxia Guan & Yanyan Ping & Huihui Fan & Yiqun Li & Hongying Zhao & Xia Li, 2012. "Discovering Dysfunction of Multiple MicroRNAs Cooperation in Disease by a Conserved MicroRNA Co-Expression Network," PLOS ONE, Public Library of Science, vol. 7(2), pages 1-11, February.
    11. Jain Yashita & Ding Shanshan & Qiu Jing, 2019. "Sliced inverse regression for integrative multi-omics data analysis," Statistical Applications in Genetics and Molecular Biology, De Gruyter, vol. 18(1), pages 1-13, February.
    12. Chen, Albert Y. & Yu, Ting-Yi, 2016. "Network based temporary facility location for the Emergency Medical Services considering the disaster induced demand and the transportation infrastructure in disaster response," Transportation Research Part B: Methodological, Elsevier, vol. 91(C), pages 408-423.
    13. Daniel G Weber & Georg Johnen & Oleksandr Bryk & Karl-Heinz Jöckel & Thomas Brüning, 2012. "Identification of miRNA-103 in the Cellular Fraction of Human Peripheral Blood as a Potential Biomarker for Malignant Mesothelioma – A Pilot Study," PLOS ONE, Public Library of Science, vol. 7(1), pages 1-9, January.
    14. Hai-Tao Zhu & Qiong-Zhu Dong & Yuan-Yuan Sheng & Jin-Wang Wei & Guan Wang & Hai-Jun Zhou & Ning Ren & Hu-Liang Jia & Qing-Hai Ye & Lun-Xiu Qin, 2012. "MicroRNA-29a-5p Is a Novel Predictor for Early Recurrence of Hepatitis B Virus-Related Hepatocellular Carcinoma after Surgical Resection," PLOS ONE, Public Library of Science, vol. 7(12), pages 1-11, December.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:19:y:2022:i:4:p:2395-:d:753263. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.