IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v19y2022i4p2050-d747706.html
   My bibliography  Save this article

Impacts of Neighborhood Characteristics and Surgical Treatment Disparities on Overall Mortality in Stage I Renal Cell Carcinoma Patients

Author

Listed:
  • Alejandro Cruz

    (Department of Urology, University of Arizona, Tucson, AZ 85724, USA)

  • Faith Dickerson

    (Department of Urology, University of Arizona, Tucson, AZ 85724, USA)

  • Kathryn R. Pulling

    (Department of Urology, University of Arizona, Tucson, AZ 85724, USA)

  • Kyle Garcia

    (Department of Urology, University of Arizona, Tucson, AZ 85724, USA)

  • Francine C. Gachupin

    (Department of Family and Community Medicine, University of Arizona, Tucson, AZ 85711, USA)

  • Chiu-Hsieh Hsu

    (Department of Epidemiology and Biostatistics, University of Arizona, Tucson, AZ 85724, USA)

  • Juan Chipollini

    (Department of Urology, University of Arizona, Tucson, AZ 85724, USA)

  • Benjamin R. Lee

    (Department of Urology, University of Arizona, Tucson, AZ 85724, USA)

  • Ken Batai

    (Department of Urology, University of Arizona, Tucson, AZ 85724, USA)

Abstract

Racial/ethnic minority groups in the United States have high renal cell carcinoma (RCC) mortality rates. This study assessed surgical treatment disparities across racial/ethnic groups and impacts of neighborhood socioeconomic characteristics on surgical treatments and overall mortality. Stage I RCC patients diagnosed between 2004 and 2016 from National Cancer Database were included (n = 238,141). We assessed differences in associations between race/ethnicity and treatment patterns using logistic regression and between race/ethnicity and overall mortality using Cox regression with and without neighborhood characteristics in the regression models. When compared to non-Hispanic Whites (NHWs), American Indians/Alaska Natives and non-Hispanic Blacks (NHBs) were more likely not to receive surgical care and all racial/ethnic minority groups had significantly increased odds of undergoing radical rather than partial nephrectomy, even after adjusting for neighborhood characteristics. Including surgical treatment and neighborhood factors in the models slightly attenuated the association, but NHBs had a significantly increased risk of overall mortality. NHBs who underwent radical nephrectomy had an increased risk of mortality (HR 1.15, 95% CI: 1.08–1.23), but not for NHBs who underwent partial nephrectomy (HR 0.92, 95% CI: 0.84–1.02). Neighborhood factors were associated with surgical treatment patterns and overall mortality in both NHBs and NHWs. Neighborhood socioeconomic factors may only partly explain RCC disparities.

Suggested Citation

  • Alejandro Cruz & Faith Dickerson & Kathryn R. Pulling & Kyle Garcia & Francine C. Gachupin & Chiu-Hsieh Hsu & Juan Chipollini & Benjamin R. Lee & Ken Batai, 2022. "Impacts of Neighborhood Characteristics and Surgical Treatment Disparities on Overall Mortality in Stage I Renal Cell Carcinoma Patients," IJERPH, MDPI, vol. 19(4), pages 1-11, February.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:4:p:2050-:d:747706
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/19/4/2050/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/19/4/2050/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Li, J. & Weir, H.K. & Jim, M.A. & King, S.M. & Wilson, R. & Master, V.A., 2014. "Kidney cancer incidence and mortality among American Indians and Alaska natives in the United States, 1990û2009," American Journal of Public Health, American Public Health Association, vol. 104(S3), pages 396-403.
    2. Amin Bemanian & Laura D. Cassidy & Raphael Fraser & Purushottam W. Laud & Kia Saeian & Kirsten M. M. Beyer, 2021. "Ecological Study of Variability in the Relationship between Liver Cancer Mortality and Racial Residential Segregation," IJERPH, MDPI, vol. 18(18), pages 1-12, September.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Francine C. Gachupin & Benjamin R. Lee & Juan Chipollini & Kathryn R. Pulling & Alejandro Cruz & Ava C. Wong & Celina I. Valencia & Chiu-Hsieh Hsu & Ken Batai, 2022. "Renal Cell Carcinoma Surgical Treatment Disparities in American Indian/Alaska Natives and Hispanic Americans in Arizona," IJERPH, MDPI, vol. 19(3), pages 1-10, January.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:19:y:2022:i:4:p:2050-:d:747706. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.