IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v19y2022i15p8919-d869187.html
   My bibliography  Save this article

Shift Work and Serum Vitamin D Levels: A Systematic Review and Meta-Analysis

Author

Listed:
  • Margherita Martelli

    (Occupational Health, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, 60126 Ancona, Italy)

  • Gianmaria Salvio

    (Endocrinology Clinic, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, 60126 Ancona, Italy)

  • Lory Santarelli

    (Occupational Health, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, 60126 Ancona, Italy)

  • Massimo Bracci

    (Occupational Health, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, 60126 Ancona, Italy)

Abstract

Vitamin D deficiency and insufficiency are highly prevalent conditions worldwide due to several factors, including poor sun exposure. Shift workers may be exposed to the risk of hypovitaminosis D due to fewer opportunities for sunlight exposure compared to day workers. A systematic review of the PubMed, SCOPUS, and EMBASE databases was conducted according to the Preferred Reporting Items for Systemic Reviews and Meta-Analyses (PRISMA) statement to investigate the effect of shift work on vitamin D levels. Mean differences (MD) and 95% confidence intervals (CI) of serum 25-OH-D levels in shift workers and non-shift workers were calculated. A total of 13 cross-sectional studies were included in the meta-analysis. We found significantly lower levels of serum 25-OH-D in shift workers compared with non-shift workers (MD: −1.85, 95% CI [−2.49 to −1.21]). Heterogeneity among included studies was high (I 2 = 89%, p < 0.0001), and neither subgroup analysis nor meta-regression were able to identify specific sources of the heterogeneity that may be related to the different characteristics of shift work among studies. The monitoring of serum vitamin D levels and prompt correction of any deficiencies should be considered in shift workers. Notably, since a large part of the observations are derived from Koreans, larger epidemiological studies are needed in other populations.

Suggested Citation

  • Margherita Martelli & Gianmaria Salvio & Lory Santarelli & Massimo Bracci, 2022. "Shift Work and Serum Vitamin D Levels: A Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 19(15), pages 1-15, July.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:15:p:8919-:d:869187
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/19/15/8919/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/19/15/8919/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Maximilian Andreas Storz & Gianluca Rizzo & Mauro Lombardo, 2022. "Shiftwork Is Associated with Higher Food Insecurity in U.S. Workers: Findings from a Cross-Sectional Study (NHANES)," IJERPH, MDPI, vol. 19(5), pages 1-14, March.
    2. Hye Yin Park & Youn-Hee Lim & Jae Bum Park & Jeongbae Rhie & Soo-Jin Lee, 2020. "Environmental and Occupation Factors Associated with Vitamin D Deficiency in Korean Adults: The Korea National Health and Nutrition Examination Survey (KNHANES) 2010–2014," IJERPH, MDPI, vol. 17(24), pages 1-11, December.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Fulvio Lauretani & Marco Salvi & Irene Zucchini & Crescenzo Testa & Chiara Cattabiani & Arianna Arisi & Marcello Maggio, 2023. "Relationship between Vitamin D and Immunity in Older People with COVID-19," IJERPH, MDPI, vol. 20(8), pages 1-19, April.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Maximilian Andreas Storz & Mauro Lombardo & Gianluca Rizzo & Alexander Müller & Ann-Kathrin Lederer, 2022. "Bowel Health in U.S. Shift Workers: Insights from a Cross-Sectional Study (NHANES)," IJERPH, MDPI, vol. 19(6), pages 1-17, March.
    2. Mi-Ra Lee & Su-Jin Han & Hee-Eun Kim & Jun-Seon Choi, 2021. "Relationship between Vitamin D Deficiency and Periodontitis in Korean Adults Aged ≥60 Years: Analysis of Data from the Korea National Health and Nutrition Examination Survey (2013–2014)," IJERPH, MDPI, vol. 18(8), pages 1-8, April.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:19:y:2022:i:15:p:8919-:d:869187. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.