IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v19y2022i13p7651-d845381.html
   My bibliography  Save this article

18F-FDG PET/CT Did Not Increase the Risk of Cataract Occurrence in Oncology Patients: A Nationwide Population-Based Cohort Study

Author

Listed:
  • Kai-Lun Cheng

    (Department of Veterinary Medicine, National Chung Hsing University, 250 Kuo Kuang Road, Taichung 40227, Taiwan
    Department of Medical Imaging, Chung Shan Medical University Hospital, 110 Jianguo North Road, Taichung 40201, Taiwan
    School of Medical Imaging and Radiological Sciences, Chung Shan Medical University, 110 Jianguo North Road, Taichung 40201, Taiwan)

  • Jing-Yang Huang

    (Center for Health Data Science, Chung Shan Medical University Hospital, 110 Jianguo North Road, Taichung 40201, Taiwan
    Institute of Medicine, College of Medicine, Chung Shan Medical University, 110 Jianguo North Road, Taichung 40201, Taiwan)

  • Jui-Hung Weng

    (Department of Nuclear Medicine, Chung Shan Medical University Hospital, 110 Jianguo North Road, Taichung 40201, Taiwan
    School of Medicine, Chung Shan Medical University, 110 Jianguo North Road, Taichung 40201, Taiwan)

  • Jeng-Yuan Chiou

    (School of Health Policy and Management, Chung Shan Medical University, 110 Jianguo North Road, Taichung 40201, Taiwan)

  • Chyn-Tair Lan

    (Department of Anatomy, Faculty of Medicine, Chung Shan Medical University, 110 Jianguo North Road, Taichung 40201, Taiwan)

  • Kwong-Chung Tung

    (Department of Veterinary Medicine, National Chung Hsing University, 250 Kuo Kuang Road, Taichung 40227, Taiwan)

Abstract

This study aimed to evaluate the risk of cataract formation associated with radiation exposure from 18F-FDG PET/CT in oncology patients, using data from Taiwan’s National Health Insurance Research Database. The exposed group (Group E) consisted of oncology patients receiving 18F-FDG PET/CT within the first year of a cancer diagnosis. The comparison group (Group C) included subjects who had never been exposed to 18F-FDG PET/CT radiation and were propensity score-matched by date of enrolment, age, sex, cancer type, associated comorbidities, and CT utilization. Multiple Cox proportional hazard regression analysis was used to estimate the hazard ratio (HR) of cataract risk due to radiation exposure, while adjusting for potential confounding factors. A total of 703 patients and 1406 matched subjects were in Groups E and C, respectively. The incidence of cataract formation was not significantly higher among subjects in Group E (adjusted HR = 1.264; 95% confidence interval [CI] = 0.845–1.891). Our results revealed that 18F-FDG PET/CT was not a significant risk factor for developing cataracts in oncology patients.

Suggested Citation

  • Kai-Lun Cheng & Jing-Yang Huang & Jui-Hung Weng & Jeng-Yuan Chiou & Chyn-Tair Lan & Kwong-Chung Tung, 2022. "18F-FDG PET/CT Did Not Increase the Risk of Cataract Occurrence in Oncology Patients: A Nationwide Population-Based Cohort Study," IJERPH, MDPI, vol. 19(13), pages 1-10, June.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:13:p:7651-:d:845381
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/19/13/7651/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/19/13/7651/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Klein, B.E.K. & Klein, R. & Linton, K.L.P. & Franke, T., 1993. "Diagnostic x-ray exposure and lens opacities: The Beaver Dam Eye Study," American Journal of Public Health, American Public Health Association, vol. 83(4), pages 588-590.
    2. Hourihan, F. & Mitchell, P. & Cumming, R.G., 1999. "Possible associations between computed tomography scan and cataract: The blue mountains eye study," American Journal of Public Health, American Public Health Association, vol. 89(12), pages 1864-1866.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.

      Corrections

      All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:19:y:2022:i:13:p:7651-:d:845381. See general information about how to correct material in RePEc.

      If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

      If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

      If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

      For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

      Please note that corrections may take a couple of weeks to filter through the various RePEc services.

      IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.