IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v18y2021i21p11045-d661173.html
   My bibliography  Save this article

Assessment of Oral Chemotherapy Nonadherence in Chronic Myeloid Leukemia Patients Using Brief Measures in Community Cancer Clinics: A Pilot Study

Author

Listed:
  • Terry C. Davis

    (Department of Medicine, Louisiana State University Health—Shreveport, Shreveport, LA 71130, USA)

  • Connie L. Arnold

    (Department of Medicine, Louisiana State University Health—Shreveport, Shreveport, LA 71130, USA)

  • Glenn Mills

    (Department of Medicine, Louisiana State University Health—Shreveport, Shreveport, LA 71130, USA)

  • Glenn J. Lesser

    (Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA)

  • W. Mark Brown

    (Department of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA)

  • Richard Schulz

    (College of Pharmacy, University of South Carolina, Columbia, SC 29208, USA)

  • Kathryn E. Weaver

    (Department of Social Sciences and Health Policy, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA)

  • Pamala A. Pawloski

    (Metro-Minnesota Community Oncology Research Consortium, St. Louis Park, MN 55416, USA)

Abstract

The purpose of this pilot study was to assess Chronic Myeloid Leukemia (CML) patients’ adherence to, beliefs about, and barriers to oral anticancer agents (OAC) using brief self-report measures in community-based cancer clinics. Patients completed a structured interview including a health literacy assessment, a Brief Medication Questionnaire, two single-item self-report adherence questions, and the Medications Adherence Reasons Scale. Of the 86 participants, 88.4% were white; 55.8% male; mean age, 58.7 years; and 22.1% had limited health literacy. Nonadherence (missing at least one dose in the last week) was reported by 18.6% of participants and associated ( p < 0.003) with less-than-excellent perceived ability to take CML medications (16.3%). Black participants reported more difficulty taking CML medications than white participants (28.6% vs. 8.3%, p = 0.053). Among all participants, 43.0% reported their CML medicine was ineffective and 24.4% that taking CML pills was somewhat to very hard. The most common reasons for missing a dose were simply missed it (24.4%) and side effects (18.6%). Most patients perceived their ability to take CML medication was good to excellent, yet nearly one in five reported missing at least one dose in the last week. Brief, no-cost self-report assessments to screen CML patients’ OAC adherence, barriers, and beliefs could facilitate counseling in busy community cancer clinics.

Suggested Citation

  • Terry C. Davis & Connie L. Arnold & Glenn Mills & Glenn J. Lesser & W. Mark Brown & Richard Schulz & Kathryn E. Weaver & Pamala A. Pawloski, 2021. "Assessment of Oral Chemotherapy Nonadherence in Chronic Myeloid Leukemia Patients Using Brief Measures in Community Cancer Clinics: A Pilot Study," IJERPH, MDPI, vol. 18(21), pages 1-12, October.
    • Handle: RePEc:gam:jijerp:v:18:y:2021:i:21:p:11045-:d:661173
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/18/21/11045/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/18/21/11045/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Theodore Darkow & Henry Henk & Simu Thomas & Weiwei Feng & Jean-Francois Baladi & George Goldberg & Alan Hatfield & Jorge Cortes, 2007. "Treatment Interruptions and Non-Adherence with Imatinib and Associated Healthcare Costs," PharmacoEconomics, Springer, vol. 25(6), pages 481-496, June.
    2. Amparo Talens & Mercedes Guilabert & Blanca Lumbreras & María Teresa Aznar & Elsa López-Pintor, 2021. "Medication Experience and Adherence to Oral Chemotherapy: A Qualitative Study of Patients’ and Health Professionals’ Perspectives," IJERPH, MDPI, vol. 18(8), pages 1-17, April.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Chou Jacquelyn W. & Lakdawalla Darius N. & Vanderpuye-Orgle Jacqueline, 2015. "Public-Private Partnership as a Path to Affordable Healthcare in Emerging Markets," Forum for Health Economics & Policy, De Gruyter, vol. 18(1), pages 65-74, January.
    2. Vicente F. Gil-Guillen & Alejandro Balsa & Beatriz Bernárdez & Carmen Valdés y Llorca & Emilio Márquez-Contreras & Juan de la Haba-Rodríguez & Jose M. Castellano & Jesús Gómez-Martínez, 2022. "Medication Non-Adherence in Rheumatology, Oncology and Cardiology: A Review of the Literature of Risk Factors and Potential Interventions," IJERPH, MDPI, vol. 19(19), pages 1-23, September.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:18:y:2021:i:21:p:11045-:d:661173. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.