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Association between Statin Use and Meniere’s Disease: Results from a National Health Screening Cohort

Author

Listed:
  • So Young Kim

    (Department of Otorhinolaryngology-Head & Neck Surgery, CHA Bundang Medical Center, CHA University, Seongnam 13496, Korea)

  • Dae Myoung Yoo

    (Hallym Data Science Laboratory, Hallym University College of Medicine, Anyang 14068, Korea)

  • Chanyang Min

    (Hallym Data Science Laboratory, Hallym University College of Medicine, Anyang 14068, Korea
    Graduate School of Public Health, Seoul National University, Seoul 08826, Korea)

  • Hyo Geun Choi

    (Hallym Data Science Laboratory, Hallym University College of Medicine, Anyang 14068, Korea
    Department of Otorhinolaryngology-Head & Neck Surgery, Hallym University College of Medicine, Anyang 14068, Korea)

Abstract

The protective effects of statins against inner ear diseases have been suggested. This study investigated the relationship between previous statin use and the occurrence of Meniere’s disease (MD). Participants ≥40 years old in the Korean National Health Insurance Service-Health Screening Cohort 2002–2015 were enrolled. A total of 7734 MD participants were matched with 38,670 comparison participants. The dates of statin prescriptions for the 2 years before the onset of MD were examined. A conditional logistic regression analysis was performed to estimate the odds ratios (ORs) of statin use for MD. Regarding the different types of statins, lipophilic statins, but not hydrophilic statins, were associated with lower odds of MD in the <65 year-old group (adjusted OR = 0.81, 95% CI = 0.68–0.97, p = 0.023). Prior statin use did not show association with MD in the adult population. Regarding the different types of statins, lipophilic statin use was related to a lower rate of MD in a middle-aged population.

Suggested Citation

  • So Young Kim & Dae Myoung Yoo & Chanyang Min & Hyo Geun Choi, 2021. "Association between Statin Use and Meniere’s Disease: Results from a National Health Screening Cohort," IJERPH, MDPI, vol. 18(16), pages 1-10, August.
    • Handle: RePEc:gam:jijerp:v:18:y:2021:i:16:p:8692-:d:616088
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    References listed on IDEAS

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    1. So Young Kim & Jee Hye Wee & Chanyang Min & Dae-Myoung Yoo & Hyo Geun Choi, 2020. "Relationship between Bell’s Palsy and Previous Statin Use: A Case/Non-Case Study," IJERPH, MDPI, vol. 17(22), pages 1-10, November.
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    Cited by:

    1. Pietro Ferrara & Luciana Albano, 2022. "Advances in Population-Based Healthcare Research: From Measures to Evidence," IJERPH, MDPI, vol. 19(20), pages 1-4, October.

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