IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v18y2021i15p8075-d604852.html
   My bibliography  Save this article

Impact of Smoking on Neutrophil Enzyme Levels in Gingivitis: A Case-Control Study

Author

Listed:
  • Rumeysa Omer-Cihangir

    (Periodontology Department, Faculty of Dentistry, University of Istanbul, Istanbul 34093, Turkey)

  • Ulku Baser

    (Periodontology Department, Faculty of Dentistry, University of Istanbul, Istanbul 34093, Turkey)

  • Canan Kucukgergin

    (Department of Medical Biochemistry, Istanbul Faculty of Medicine, University of Istanbul, Istanbul 34093, Turkey)

  • Gokce Aykol-Sahin

    (Periodontology Department, Faculty of Dentistry, Istanbul Okan University, Istanbul 34959, Turkey)

  • Olivier Huck

    (Department of Periodontology, Dental Faculty, University of Strasbourg, 67081 Strasbourg, France
    INSERM, UMR 1260 Osteoarticular and Dental Regenerative Nanomedicine, 67000 Strasbourg, France
    Pôle de Médecine et de Chirurgie Bucco-Dentaires, Hôpitaux Universitaires de Strasbourg, 67091 Strasbourg, France)

  • Funda Yalcin

    (Periodontology Department, Faculty of Dentistry, University of Istanbul, Istanbul 34093, Turkey)

Abstract

Background: The determination of the impact of risk factors such as smoking in periodontal disease development is of importance to better characterize the disease. However, its impact on host response remains unclear. This study aimed to evaluate the effects of tobacco smoking on GCF levels of neutrophil enzymes (myeloperoxidase (MPO), beta-glucuronidase (BGD), neutrophil elastase (NE) and periodontal parameters in healthy young adults with dental plaque biofilm-induced gingivitis. Methods: The study population consisted of 60 systemically healthy young adults (39 smokers (Sm) and 21 non-smokers (n-Sm)) diagnosed with plaque-induced gingivitis. The periodontal examination consisted of a plaque index (PI); gingival index (GI); probing depth (PD); bleeding on probing (BoP), and clinical attachment level (CAL). GCF MPO, BGD, and NE levels were determined by means of an enzyme-linked immunosorbent assay (ELISA). Results: PI, GI, and BoP were significantly increased in the Sm group ( p < 0.05). PD and CAL showed no significant difference between Sm and n -Sm groups ( p > 0.05). In GCF, MPO, BGD, and NE levels were significantly increased in Sm group ( p < 0.05). NE levels showed a significant correlation with GI and BoP ( p < 0.05 for both). Moreover, a positive correlation between BGD and NE levels ( p < 0.05) was measured. Conclusions: It may be concluded that, even in young patients, tobacco consumption affects the host’s immune response related to gingival inflammation. It is, therefore, mandatory to inform young patients about the risk related to tobacco consumption for their gingival health.

Suggested Citation

  • Rumeysa Omer-Cihangir & Ulku Baser & Canan Kucukgergin & Gokce Aykol-Sahin & Olivier Huck & Funda Yalcin, 2021. "Impact of Smoking on Neutrophil Enzyme Levels in Gingivitis: A Case-Control Study," IJERPH, MDPI, vol. 18(15), pages 1-9, July.
    • Handle: RePEc:gam:jijerp:v:18:y:2021:i:15:p:8075-:d:604852
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/18/15/8075/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/18/15/8075/
    Download Restriction: no
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Catherine Petit & Victor Anadon-Rosinach & Nicolas Tuzin & Jean-Luc Davideau & Olivier Huck, 2021. "Influence of Depression and Anxiety on Non-Surgical Periodontal Treatment Outcomes: A 6-Month Prospective Study," IJERPH, MDPI, vol. 18(17), pages 1-10, September.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:18:y:2021:i:15:p:8075-:d:604852. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.