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Current Status of Mumps Virus Infection: Epidemiology, Pathogenesis, and Vaccine

Author

Listed:
  • Shih-Bin Su

    (Department of Occupational Medicine, Chi-Mei Medical Center, Tainan 710, Taiwan)

  • Hsiao-Liang Chang

    (Department of Surveillance, Centers for Disease Control, Taipei 100, Taiwan)

  • Kow-Tong Chen

    (Department of Occupational Medicine, Tainan Municipal Hospital (managed by Show Chwan Medical Care Corporation), Tainan 701, Taiwan
    Department of Public Health, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan)

Abstract

Mumps is an important childhood infectious disease caused by mumps virus (MuV). We reviewed the epidemiology, pathogenesis, and vaccine development of mumps. Previous studies were identified using the key words “mumps” and “epidemiology”, “pathogenesis” or “vaccine” in MEDLINE, PubMed, Embase, Web of Science, and Google Scholar. We excluded the articles that were not published in the English language, manuscripts without abstracts, and opinion articles from the review. The number of cases caused by MuV decreased steeply after the introduction of the mumps vaccine worldwide. In recent years, a global resurgence of mumps cases in developed countries and cases of aseptic meningitis caused by some mumps vaccine strains have renewed the importance of MuV infection worldwide. The performance of mumps vaccination has become an important issue for controlling mumps infections. Vaccine development and routine vaccination are still effective measures to globally reduce the incidence of mumps infections. During outbreaks, a third of MMR vaccine is recommended for groups of persons determined by public authorities.

Suggested Citation

  • Shih-Bin Su & Hsiao-Liang Chang & Kow-Tong Chen, 2020. "Current Status of Mumps Virus Infection: Epidemiology, Pathogenesis, and Vaccine," IJERPH, MDPI, vol. 17(5), pages 1-15, March.
    • Handle: RePEc:gam:jijerp:v:17:y:2020:i:5:p:1686-:d:328841
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    Cited by:

    1. Chunghyeon Oh & Eric Rafai & Yinseo Cho & Damin Jun & Seungman Cha, 2022. "An Economic Analysis of Mumps Vaccination in Fiji: Static Model Simulation of Routine Measles–Mumps–Rubella (MMR) Vaccination Instead of Current Measles–Rubella (MR) Vaccination," IJERPH, MDPI, vol. 19(3), pages 1-12, February.

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