IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v17y2020i2p546-d308878.html
   My bibliography  Save this article

Long-Term Effects of Air Pollutants on Mortality Risk in Patients with End-Stage Renal Disease

Author

Listed:
  • Jiyun Jung

    (Department of Biostatistics and Epidemiology, School of Public Health, Seoul National University, Seoul 08826, Korea
    These authors contributed equally to this work.)

  • Jae Yoon Park

    (Department of Internal Medicine, Dongguk University Ilsan Hospital, Gyeonggi-do 10326, Korea
    Department of Internal Medicine, Dongguk University College of Medicine, Gyeongsangbuk-do 38066, Korea
    These authors contributed equally to this work.)

  • Yong Chul Kim

    (Department of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Korea)

  • Hyewon Lee

    (Department of Neuropsychiatry, Seoul National University Bundang Hospital, Gyeonggi-do 13620, Korea
    Institute of Health and Environment, Seoul National University, Seoul 08826, Korea)

  • Ejin Kim

    (Department of Biostatistics and Epidemiology, School of Public Health, Seoul National University, Seoul 08826, Korea)

  • Yong-Lim Kim

    (Department of Internal Medicine, Kyungpook National University College of Medicine, Daegu 41566, Korea)

  • Yon Su Kim

    (Department of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Korea)

  • Jung Pyo Lee

    (Department of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Korea
    Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul 07061, Korea)

  • Ho Kim

    (Department of Biostatistics and Epidemiology, School of Public Health, Seoul National University, Seoul 08826, Korea)

  • Clinical Research Center for End-Stage Renal Disease (CRC for ESRD) Investigators

    (These authors are mentioned in Acknowledgments.)

Abstract

Long-term exposure to air pollutants significantly increases the morbidity and mortality associated with various diseases. However, little is known about the relationship between air pollutants and end-stage renal disease (ESRD)-related mortality. A total of 5041 patients who started dialysis between 2008 and 2015 were prospectively enrolled in the Clinical Research Center for End-Stage Renal Disease (CRC-ESRD) cohort study. We assigned a daily mean concentration of air pollutants (PM 10 , NO 2 , and SO 2 ) to each participant. Time-varying Cox models were used to investigate the relationship between air pollutants and mortality in ESRD patients. During the follow-up period (mean 4.18 years), 1475 deaths occurred among 5041 participants. We found a significant long-term relationship between mortality risk and PM 10 (HR 1.33, CI 1.13–1.58), NO 2 (HR 1.46, CI 1.10–1.95), and SO 2 (HR 1.07, CI 1.03–1.11). Elderly patients and patients who lived in metropolitan areas had an increased risk associated with PM 10 . Elderly patients also had increased risks associated NO 2 and SO 2 . Long-term exposure to air pollutants had negative effects on mortality in ESRD patients. These effects were prominent in elderly patients who lived in metropolitan areas, suggesting that ambient air pollution, in addition to traditional risk factors, is important for the survival of these patients.

Suggested Citation

  • Jiyun Jung & Jae Yoon Park & Yong Chul Kim & Hyewon Lee & Ejin Kim & Yong-Lim Kim & Yon Su Kim & Jung Pyo Lee & Ho Kim & Clinical Research Center for End-Stage Renal Disease (CRC for ESRD) Investigato, 2020. "Long-Term Effects of Air Pollutants on Mortality Risk in Patients with End-Stage Renal Disease," IJERPH, MDPI, vol. 17(2), pages 1-12, January.
    • Handle: RePEc:gam:jijerp:v:17:y:2020:i:2:p:546-:d:308878
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/17/2/546/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/17/2/546/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Ching-Chang Cho & Wen-Yeh Hsieh & Chin-Hung Tsai & Cheng-Yi Chen & Hui-Fang Chang & Chih-Sheng Lin, 2018. "In Vitro and In Vivo Experimental Studies of PM 2.5 on Disease Progression," IJERPH, MDPI, vol. 15(7), pages 1-26, July.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Yuanni Huang & Mian Bao & Jiefeng Xiao & Zhaolong Qiu & Kusheng Wu, 2019. "Effects of PM 2.5 on Cardio-Pulmonary Function Injury in Open Manganese Mine Workers," IJERPH, MDPI, vol. 16(11), pages 1-10, June.
    2. Yueming Wen & Jiawei Leng & Xiaobing Shen & Gang Han & Lijun Sun & Fei Yu, 2020. "Environmental and Health Effects of Ventilation in Subway Stations: A Literature Review," IJERPH, MDPI, vol. 17(3), pages 1-37, February.
    3. Daoru Liu & Qinli Deng & Zeng Zhou & Yaolin Lin & Junwei Tao, 2018. "Variation Trends of Fine Particulate Matter Concentration in Wuhan City from 2013 to 2017," IJERPH, MDPI, vol. 15(7), pages 1-18, July.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:17:y:2020:i:2:p:546-:d:308878. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.