IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v17y2020i24p9538-d465214.html
   My bibliography  Save this article

Incidence and Survival Trends of Pancreatic Cancer in Girona: Impact of the Change in Patient Care in the Last 25 Years

Author

Listed:
  • Adelaida García-Velasco

    (Medical Oncology Department, Josep Trueta Universitary Hospital, Catalan Institute of Oncology, Av de França, 17007 Girona, Spain
    Descriptive Epidemiology, Genetics and Cancer Prevention Group, Biomedical Research Institute (IDIBGI), C/Dr. Castany, s/n, 17190 Salt, Spain)

  • Lluís Zacarías-Pons

    (Epidemiology Unit and Girona Cancer Registry, Oncology Coordination Plan, Department of Health, Autonomous Government of Catalonia, Catalan Institute of Oncology, Av. França, s/n, 17004 Girona, Spain)

  • Helena Teixidor

    (Epidemiology Unit and Girona Cancer Registry, Oncology Coordination Plan, Department of Health, Autonomous Government of Catalonia, Catalan Institute of Oncology, Av. França, s/n, 17004 Girona, Spain)

  • Marc Valeros

    (Epidemiology Unit and Girona Cancer Registry, Oncology Coordination Plan, Department of Health, Autonomous Government of Catalonia, Catalan Institute of Oncology, Av. França, s/n, 17004 Girona, Spain)

  • Raquel Liñan

    (Medical Oncology Department, Josep Trueta Universitary Hospital, Catalan Institute of Oncology, Av de França, 17007 Girona, Spain)

  • M. Carmen Carmona-Garcia

    (Medical Oncology Department, Josep Trueta Universitary Hospital, Catalan Institute of Oncology, Av de França, 17007 Girona, Spain
    Descriptive Epidemiology, Genetics and Cancer Prevention Group, Biomedical Research Institute (IDIBGI), C/Dr. Castany, s/n, 17190 Salt, Spain)

  • Montse Puigdemont

    (Descriptive Epidemiology, Genetics and Cancer Prevention Group, Biomedical Research Institute (IDIBGI), C/Dr. Castany, s/n, 17190 Salt, Spain
    Epidemiology Unit and Girona Cancer Registry, Oncology Coordination Plan, Department of Health, Autonomous Government of Catalonia, Catalan Institute of Oncology, Av. França, s/n, 17004 Girona, Spain)

  • Walter Carbajal

    (Medical Oncology Department, Josep Trueta Universitary Hospital, Catalan Institute of Oncology, Av de França, 17007 Girona, Spain)

  • Raquel Guardeño

    (Medical Oncology Department, Josep Trueta Universitary Hospital, Catalan Institute of Oncology, Av de França, 17007 Girona, Spain)

  • Núria Malats

    (Genetic and Molecular Epidemiology Group, Spanish National Cancer Research (CNIO) and CIBERONC, 28029 Madrid, Spain)

  • Eric Duell

    (Unit of Biomarkers and Susceptibility, Oncology Data Analytics Program, Catalan Institute of Oncology (ICO), Colorectal Cancer Group, ONCOBELL Program, Bellvitge Biomedical Research Institute (IDIBELL), L’Hospitalet de Llobregat, Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), 08908 Barcelona, Spain)

  • Rafael Marcos-Gragera

    (Descriptive Epidemiology, Genetics and Cancer Prevention Group, Biomedical Research Institute (IDIBGI), C/Dr. Castany, s/n, 17190 Salt, Spain
    Epidemiology Unit and Girona Cancer Registry, Oncology Coordination Plan, Department of Health, Autonomous Government of Catalonia, Catalan Institute of Oncology, Av. França, s/n, 17004 Girona, Spain
    Consortium for Biomedical Research in Epidemiology and Public Health (CIBER Epidemiología y Salud Pública, CIBERESP), 28029 Madrid, Spain)

Abstract

(1) Background: We investigated the incidence and survival trends for pancreatic cancer (PC) over the last 25 years in the Girona region, Catalonia, Spain; (2) Methods: Data were extracted from the population-based Girona Cancer Registry. Incident PC cases during 1994–2015 were classified using the International Classification of Diseases for Oncology Third Edition (ICD-O-3). Incidence rates age-adjusted to the European standard population (ASR E ) and world standard population (ASR W ) were obtained. Trends were assessed using the estimated annual percentage of change (EAPC) of the ASR E13. Observed and relative survivals (RS) were estimated with the Kaplan–Meier and Pohar Perme methods, respectively; (3) Results: We identified 1602 PC incident cases. According to histology, 44.4% of cases were exocrine PC, 4.1% neuroendocrine, and 51.1% malignant-non-specified. The crude incidence rate (CR) for PC was 11.43 cases-per-100,000 inhabitants/year. A significant increase of incidence with age and over the study period was observed. PC overall 5-year RS was 7.05% (95% confidence interval (CI) 5.63; 8.84). Longer overall survival was observed in patients with neuroendocrine tumours (5-year RS 61.45%; 95% CI 47.47; 79.55). Trends in 5-year RS for the whole cohort rose from 3.27% (95% CI 1.69–6.35) in 1994–1998 to 13.1% (95% CI 9.98; 17.2) in 2010–2015; (4) Conclusions: Incidence rates of PC in Girona have increased in the last two decades. There is a moderate but encouraging increase in survival thorough the study period. These results can be used as baseline for future research.

Suggested Citation

  • Adelaida García-Velasco & Lluís Zacarías-Pons & Helena Teixidor & Marc Valeros & Raquel Liñan & M. Carmen Carmona-Garcia & Montse Puigdemont & Walter Carbajal & Raquel Guardeño & Núria Malats & Eric D, 2020. "Incidence and Survival Trends of Pancreatic Cancer in Girona: Impact of the Change in Patient Care in the Last 25 Years," IJERPH, MDPI, vol. 17(24), pages 1-22, December.
    • Handle: RePEc:gam:jijerp:v:17:y:2020:i:24:p:9538-:d:465214
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/17/24/9538/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/17/24/9538/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Paul W. Dickman & Enzo Coviello, 2015. "Estimating and modeling relative survival," Stata Journal, StataCorp LP, vol. 15(1), pages 186-215, March.
    2. Maja Pohar Perme & Janez Stare & Jacques Estève, 2012. "On Estimation in Relative Survival," Biometrics, The International Biometric Society, vol. 68(1), pages 113-120, March.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Laura Guarga & Noelia Paco & Paula Manchon-Walsh & Emili Vela & Joaquim Delgadillo & Caridad Pontes & Josep Maria Borràs, 2023. "Management, Survival, and Costs of Pancreatic Cancer: Population-Based Observational Study in Catalonia," IJERPH, MDPI, vol. 20(9), pages 1-15, April.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Jonviea D. Chamberlain & Anne Buzzell & Hans Peter Gmünder & Kerstin Hug & Xavier Jordan & André Moser & Martin Schubert & Marcel Zwahlen & Martin W. G. Brinkhof, 2019. "Excess burden of a chronic disabling condition: life lost due to traumatic spinal cord injury in a Swiss population-based cohort study," International Journal of Public Health, Springer;Swiss School of Public Health (SSPH+), vol. 64(7), pages 1097-1105, September.
    2. Peter Cnudde & Szilard Nemes & Maziar Mohaddes & John Timperley & Göran Garellick & Kristina Burström & Ola Rolfson, 2017. "Is Preoperative Patient-Reported Health Status Associated with Mortality after Total Hip Replacement?," IJERPH, MDPI, vol. 14(8), pages 1-13, August.
    3. Sho Komukai & Satoshi Hattori, 2017. "Doubly robust estimator for net survival rate in analyses of cancer registry data," Biometrics, The International Biometric Society, vol. 73(1), pages 124-133, March.
    4. Ged Dempsey & Dan Hungerford & Phil McHale & Lauren McGarey & Edward Benison & Ben Morton, 2020. "Long term outcomes for elderly patients after emergency intensive care admission: A cohort study," PLOS ONE, Public Library of Science, vol. 15(10), pages 1-14, October.
    5. Francisco Carrasco-Peña & Eloisa Bayo-Lozano & Miguel Rodríguez-Barranco & Dafina Petrova & Rafael Marcos-Gragera & Maria Carmen Carmona-Garcia & Josep Maria Borras & Maria-José Sánchez, 2020. "Adherence to Clinical Practice Guidelines and Colorectal Cancer Survival: A Retrospective High-Resolution Population-Based Study in Spain," IJERPH, MDPI, vol. 17(18), pages 1-15, September.
    6. Nicolas Bovio & Michel Grzebyk & Patrick Arveux & Jean-Luc Bulliard & Arnaud Chiolero & Evelyne Fournier & Simon Germann & Isabelle Konzelmann & Manuela Maspoli & Elisabetta Rapiti & Irina Guseva Canu, 2022. "Work-Related Factors and Lung Cancer Survival: A Population-Based Study in Switzerland (1990–2014)," IJERPH, MDPI, vol. 19(21), pages 1-16, October.
    7. Olayidé Boussari & Laurent Bordes & Gaëlle Romain & Marc Colonna & Nadine Bossard & Laurent Remontet & Valérie Jooste, 2021. "Modeling excess hazard with time‐to‐cure as a parameter," Biometrics, The International Biometric Society, vol. 77(4), pages 1289-1302, December.
    8. Alessia Eletti & Giampiero Marra & Manuela Quaresma & Rosalba Radice & Francisco Javier Rubio, 2022. "A unifying framework for flexible excess hazard modelling with applications in cancer epidemiology," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 71(4), pages 1044-1062, August.
    9. Alicia Villavicencio & Marta Solans & Lluís Zacarías-Pons & Anna Vidal & Montse Puigdemont & Josep Maria Roncero & Marc Saez & Rafael Marcos-Gragera, 2021. "Comorbidities at Diagnosis, Survival, and Cause of Death in Patients with Chronic Lymphocytic Leukemia: A Population-Based Study," IJERPH, MDPI, vol. 18(2), pages 1-10, January.
    10. Peter Sasieni & Adam R. Brentnall, 2017. "On standardized relative survival," Biometrics, The International Biometric Society, vol. 73(2), pages 473-482, June.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:17:y:2020:i:24:p:9538-:d:465214. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.