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“Good Epidemiology Practice” Guidelines for Pesticide Exposure Assessment

Author

Listed:
  • Julie E. Goodman

    (Gradient, One Beacon Street, 17th Floor, Boston, MA 02108, USA)

  • Robyn L. Prueitt

    (Gradient, 600 Stewart Street, Suite 1900, Seattle, WA 98101, USA)

  • Paolo Boffetta

    (Stony Brook Cancer Center, Department of Family, Population and Preventive Medicine, Stony Brook University, Stony Brook, NY 11794, USA
    Department of Medical and Surgical Sciences, University of Bologna, 40126 Bologna, Italy)

  • Crispin Halsall

    (Lancaster Environment Center, Lancaster University, Lancaster LA1 4YQ, UK)

  • Andrew Sweetman

    (Lancaster Environment Center, Lancaster University, Lancaster LA1 4YQ, UK)

Abstract

Both toxicology and epidemiology are used to inform hazard and risk assessment in regulatory settings, particularly for pesticides. While toxicology studies involve controlled, quantifiable exposures that are often administered according to standardized protocols, estimating exposure in observational epidemiology studies is challenging, and there is no established guidance for doing so. However, there are several frameworks for evaluating the quality of published epidemiology studies. We previously developed a preliminary list of methodology and reporting standards for epidemiology studies, called Good Epidemiology Practice (GEP) guidelines, based on a critical review of standardized toxicology protocols and available frameworks for evaluating epidemiology study quality. We determined that exposure characterization is one of the most critical areas for which standards are needed. Here, we propose GEP guidelines for pesticide exposure assessment based on the source of exposure data (i.e., biomonitoring and environmental samples, questionnaire/interview/expert record review, and dietary exposures based on measurements of residues in food and food consumption). It is expected that these GEP guidelines will facilitate the conduct of higher-quality epidemiology studies that can be used as a basis for more scientifically sound regulatory risk assessment and policy making.

Suggested Citation

  • Julie E. Goodman & Robyn L. Prueitt & Paolo Boffetta & Crispin Halsall & Andrew Sweetman, 2020. "“Good Epidemiology Practice” Guidelines for Pesticide Exposure Assessment," IJERPH, MDPI, vol. 17(14), pages 1-15, July.
  • Handle: RePEc:gam:jijerp:v:17:y:2020:i:14:p:5114-:d:385047
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    References listed on IDEAS

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    1. Nigl Paneth & Ezra Susser & Mervyn Susser, 2002. "Origins and early development of the case-control study: part 2, The case-control study from Lane-Claypon to 1950," International Journal of Public Health, Springer;Swiss School of Public Health (SSPH+), vol. 47(6), pages 359-365, December.
    2. Nigel Paneth & Ezra Susser & Mervyn Susser, 2002. "Origins and early development of the case-control study: part 1, Early evolution," International Journal of Public Health, Springer;Swiss School of Public Health (SSPH+), vol. 47(5), pages 282-288, November.
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    Cited by:

    1. Jessika Barrón Cuenca & Kristian Dreij & Noemi Tirado, 2024. "Human Pesticide Exposure in Bolivia: A Scoping Review of Current Knowledge, Future Challenges and Research Needs," IJERPH, MDPI, vol. 21(3), pages 1-17, March.

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