IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v17y2020i10p3358-d357096.html
   My bibliography  Save this article

Initiation and Single Dispensing in Cardiovascular and Insulin Medications: Prevalence and Explanatory Factors

Author

Listed:
  • Carles Vilaplana-Carnerero

    (Research and Development Unit, Institut de Recerca Sant Joan de Déu, 08830 Barcelona, Catalonia, Spain
    School of Pharmacy, University of Barcelona, 08028 Barcelona, Catalonia, Spain)

  • Ignacio Aznar-Lou

    (Research and Development Unit, Institut de Recerca Sant Joan de Déu, 08830 Barcelona, Catalonia, Spain
    Consortium for Biomedical Research in Epidemiology & Public Health (CIBER en Epidemiología y Salud Pública—CIBERESP), 28029 Madrid, Spain)

  • María Teresa Peñarrubia-María

    (Consortium for Biomedical Research in Epidemiology & Public Health (CIBER en Epidemiología y Salud Pública—CIBERESP), 28029 Madrid, Spain
    Primary Care Research Institute (IDIAP Jordi Gol), 08007 Barcelona, Spain
    Catalan Institute of Health, 08028 Barcelona, Spain)

  • Antoni Serrano-Blanco

    (Consortium for Biomedical Research in Epidemiology & Public Health (CIBER en Epidemiología y Salud Pública—CIBERESP), 28029 Madrid, Spain
    Parc Sanitari Sant Joan de Déu, 08830 Sant Boi de Llobregat, Catalonia, Spain)

  • Rita Fernández-Vergel

    (Primary Care Research Institute (IDIAP Jordi Gol), 08007 Barcelona, Spain
    Catalan Institute of Health, 08028 Barcelona, Spain)

  • Dolors Petitbò-Antúnez

    (Catalan Institute of Health, 08028 Barcelona, Spain)

  • Montserrat Gil-Girbau

    (Research and Development Unit, Institut de Recerca Sant Joan de Déu, 08830 Barcelona, Catalonia, Spain
    School of Pharmacy, University of Barcelona, 08028 Barcelona, Catalonia, Spain
    Primary Care Prevention and Health Promotion Research Network, 08007 Barcelona, Catalonia, Spain)

  • Marian March-Pujol

    (School of Pharmacy, University of Barcelona, 08028 Barcelona, Catalonia, Spain
    Consortium for Biomedical Research in Epidemiology & Public Health (CIBER en Epidemiología y Salud Pública—CIBERESP), 28029 Madrid, Spain)

  • Juan Manuel Mendive

    (Primary Care Research Institute (IDIAP Jordi Gol), 08007 Barcelona, Spain
    Catalan Institute of Health, 08028 Barcelona, Spain
    Primary Care Prevention and Health Promotion Research Network, 08007 Barcelona, Catalonia, Spain)

  • Alba Sánchez-Viñas

    (Research and Development Unit, Institut de Recerca Sant Joan de Déu, 08830 Barcelona, Catalonia, Spain)

  • Cristina Carbonell-Duacastella

    (Research and Development Unit, Institut de Recerca Sant Joan de Déu, 08830 Barcelona, Catalonia, Spain
    Consortium for Biomedical Research in Epidemiology & Public Health (CIBER en Epidemiología y Salud Pública—CIBERESP), 28029 Madrid, Spain)

  • Maria Rubio-Valera

    (Consortium for Biomedical Research in Epidemiology & Public Health (CIBER en Epidemiología y Salud Pública—CIBERESP), 28029 Madrid, Spain
    Parc Sanitari Sant Joan de Déu, 08830 Sant Boi de Llobregat, Catalonia, Spain)

Abstract

Background: Adherence problems have negative effects on health, but there is little information on the magnitude of non-initiation and single dispensing. Objective: The aim of this study was to estimate the prevalence of non-initiation and single dispensation and identify associated predictive factors for the main treatments prescribed in Primary Care (PC) for cardiovascular disease (CVD) and diabetes. Methods: Cohort study with real-world data. Patients who received a first prescription (2013–2014) for insulins, platelet aggregation inhibitors, angiotensin-converting enzyme inhibitors (ACEI) or statins in Catalan PC were included. The prevalence of non-initiation and single dispensation was calculated. Factors that explained these behaviours were explored. Results: At three months, between 5.7% (ACEI) and 9.1% (antiplatelets) of patients did not initiate their treatment and between 10.6% (statins) and 18.4% (ACEI) filled a single prescription. Body mass index, previous CVD, place of origin and having a substitute prescriber, among others, influenced the risk of non-initiation and single dispensation. Conclusions: The prevalence of non-initiation and single dispensation of CVD medications and insulin prescribed in PC in is high. Patient and health-system factors, such as place of origin and type of prescriber, should be taken into consideration when prescribing new medications for CVD and diabetes.

Suggested Citation

  • Carles Vilaplana-Carnerero & Ignacio Aznar-Lou & María Teresa Peñarrubia-María & Antoni Serrano-Blanco & Rita Fernández-Vergel & Dolors Petitbò-Antúnez & Montserrat Gil-Girbau & Marian March-Pujol & J, 2020. "Initiation and Single Dispensing in Cardiovascular and Insulin Medications: Prevalence and Explanatory Factors," IJERPH, MDPI, vol. 17(10), pages 1-17, May.
    • Handle: RePEc:gam:jijerp:v:17:y:2020:i:10:p:3358-:d:357096
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/17/10/3358/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/17/10/3358/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Azzurra Massimi & Corrado De Vito & Ilaria Brufola & Alice Corsaro & Carolina Marzuillo & Giuseppe Migliara & Maria Luisa Rega & Walter Ricciardi & Paolo Villari & Gianfranco Damiani, 2017. "Are community-based nurse-led self-management support interventions effective in chronic patients? Results of a systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 12(3), pages 1-22, March.
    2. Pound, Pandora & Britten, Nicky & Morgan, Myfanwy & Yardley, Lucy & Pope, Catherine & Daker-White, Gavin & Campbell, Rona, 2005. "Resisting medicines: a synthesis of qualitative studies of medicine taking," Social Science & Medicine, Elsevier, vol. 61(1), pages 133-155, July.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Allison Williams & Jac Kee Low & Elizabeth Manias & Kimberley Crawford, 2016. "The transplant team's support of kidney transplant recipients to take their prescribed medications: a collective responsibility," Journal of Clinical Nursing, John Wiley & Sons, vol. 25(15-16), pages 2251-2261, August.
    2. Rebecca J Bartlett Ellis & Janet L Welch, 2017. "Medication‐taking behaviours in chronic kidney disease with multiple chronic conditions: a meta‐ethnographic synthesis of qualitative studies," Journal of Clinical Nursing, John Wiley & Sons, vol. 26(5-6), pages 586-598, March.
    3. Jyh-Jeng Wu & Yueh-Mei Chen & Paul C. Talley & Kuang-Ming Kuo, 2021. "Does Online Community Participation Contribute to Medication Adherence? An Empirical Study of Patients with Chronic Diseases," IJERPH, MDPI, vol. 18(10), pages 1-16, May.
    4. Dew, Kevin & Norris, Pauline & Gabe, Jonathan & Chamberlain, Kerry & Hodgetts, Darrin, 2015. "Moral discourses and pharmaceuticalised governance in households," Social Science & Medicine, Elsevier, vol. 131(C), pages 272-279.
    5. Brigitte Woo & Karen Koh & Wentao Zhou & Toon Wei Lim & Violeta Lopez & Wilson Tam, 2020. "Understanding the role of an advanced practice nurse through the perspectives of patients with cardiovascular disease: A qualitative study," Journal of Clinical Nursing, John Wiley & Sons, vol. 29(9-10), pages 1623-1634, May.
    6. Gabe, Jonathan & Williams, Simon J. & Coveney, Catherine M., 2017. "Prescription hypnotics in the news: A study of UK audiences," Social Science & Medicine, Elsevier, vol. 174(C), pages 43-52.
    7. Webster, Michelle, 2017. "Similarities and differences in the meanings children and their parents attach to epilepsy medications," Social Science & Medicine, Elsevier, vol. 177(C), pages 190-197.
    8. Ridge, Damien & Kokanovic, Renata & Broom, Alex & Kirkpatrick, Susan & Anderson, Claire & Tanner, Claire, 2015. "“My dirty little habit”: Patient constructions of antidepressant use and the ‘crisis’ of legitimacy," Social Science & Medicine, Elsevier, vol. 146(C), pages 53-61.
    9. Gibson, Grant, 2016. "‘Signposts on the journey’; medication adherence and the lived body in men with Parkinson's disease," Social Science & Medicine, Elsevier, vol. 152(C), pages 27-34.
    10. Berry, Brandon & Apesoa-Varano, Ester Carolina, 2017. "Medication takeovers: Covert druggings and behavioral control in Alzheimer's," Social Science & Medicine, Elsevier, vol. 188(C), pages 51-59.
    11. Ceuterick, Melissa & Vandebroek, Ina, 2017. "Identity in a medicine cabinet: Discursive positions of Andean migrants towards their use of herbal remedies in the United Kingdom," Social Science & Medicine, Elsevier, vol. 177(C), pages 43-51.
    12. Klein, Linda A. & Ritchie, Jan E. & Nathan, Sally & Wutzke, Sonia, 2014. "An explanatory model of peer education within a complex medicines information exchange setting," Social Science & Medicine, Elsevier, vol. 111(C), pages 101-109.
    13. Allen, Dawn & Wainwright, Megan & Hutchinson, Thomas, 2011. "'Non-compliance' as illness management: Hemodialysis patients' descriptions of adversarial patient-clinician interactions," Social Science & Medicine, Elsevier, vol. 73(1), pages 129-134, July.
    14. Schweda, Mark & Pfaller, Larissa, 2014. "Colonization of later life? Laypersons' and users' agency regarding anti-aging medicine in Germany," Social Science & Medicine, Elsevier, vol. 118(C), pages 159-165.
    15. Persson, Asha & Newman, Christy, 2006. "Potency and vulnerability: Troubled 'selves' in the context of antiretroviral therapy," Social Science & Medicine, Elsevier, vol. 63(6), pages 1586-1596, September.
    16. Timmermans, Stefan & Tietbohl, Caroline, 2018. "Fifty years of sociological leadership at Social Science and Medicine," Social Science & Medicine, Elsevier, vol. 196(C), pages 209-215.
    17. Nakata, Cheryl & Sharp, Lisa K. & Spanjol, Jelena & Cui, Anna Shaojie & Izberk-Bilgin, Elif & Crawford, Stephanie Y. & Xiao, Yazhen, 2021. "Narrative arcs and shaping influences in long-term medication adherence," Social Science & Medicine, Elsevier, vol. 285(C).
    18. Will, Catherine M. & Weiner, Kate, 2015. "The drugs don't sell: DIY heart health and the over-the-counter statin experience," Social Science & Medicine, Elsevier, vol. 131(C), pages 280-288.
    19. Goldsmith, Laurie J. & Kolhatkar, Ashra & Popowich, Dominic & Holbrook, Anne M. & Morgan, Steven G. & Law, Michael R., 2017. "Understanding the patient experience of cost-related non-adherence to prescription medications through typology development and application," Social Science & Medicine, Elsevier, vol. 194(C), pages 51-59.
    20. Rachel A. Crockett & Stephen Sutton & Fiona M. Walter & Megan Clinch & Theresa M. Marteau & John Benson, 2011. "Impact on Decisions to Start or Continue Medicines of Providing Information to Patients about Possible Benefits and/or Harms," Medical Decision Making, , vol. 31(5), pages 767-777, September.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:17:y:2020:i:10:p:3358-:d:357096. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.