IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v16y2019i13p2253-d242970.html
   My bibliography  Save this article

Antibiotic Consumption and Resistance during a 3-Year Period in Sicily, Southern Italy

Author

Listed:
  • Martina Barchitta

    (Department of Medical and Surgical Sciences and Advanced Technologies “GF Ingrassia”, University of Catania, 95123 Catania, Italy)

  • Annalisa Quattrocchi

    (Department of Medical and Surgical Sciences and Advanced Technologies “GF Ingrassia”, University of Catania, 95123 Catania, Italy)

  • Andrea Maugeri

    (Department of Medical and Surgical Sciences and Advanced Technologies “GF Ingrassia”, University of Catania, 95123 Catania, Italy)

  • Maria Clara La Rosa

    (Department of Medical and Surgical Sciences and Advanced Technologies “GF Ingrassia”, University of Catania, 95123 Catania, Italy)

  • Claudia La Mastra

    (Department of Medical and Surgical Sciences and Advanced Technologies “GF Ingrassia”, University of Catania, 95123 Catania, Italy)

  • Laura Sessa

    (Department of Medical and Surgical Sciences and Advanced Technologies “GF Ingrassia”, University of Catania, 95123 Catania, Italy)

  • Pasquale Cananzi

    (Regional Health Authority of the Sicilian Region, 90145 Palermo, Italy)

  • Giuseppe Murolo

    (Regional Health Authority of the Sicilian Region, 90145 Palermo, Italy)

  • Alessandro Oteri

    (Regional Health Authority of the Sicilian Region, 90145 Palermo, Italy)

  • Guido Basile

    (Department of General Surgery and Medical-Surgical Specialties, University of Catania, 95123 Catania, Italy)

  • Antonella Agodi

    (Department of Medical and Surgical Sciences and Advanced Technologies “GF Ingrassia”, University of Catania, 95123 Catania, Italy
    AOU Policlinico-Vittorio Emanuele, 95123 Catania, Italy)

Abstract

Antimicrobial resistance (AMR) is one of the biggest issues facing global public health. In 2017, Italy adopted its first National Action Plan on Antimicrobial Resistance 2017–2020, which works through the synergy between national, regional, and local levels. In the framework of a Regional Action Plan on healthcare-associated infections and AMR prevention, the Sicilian Health Authority of the Sicilian Region, Southern Italy, has implemented a surveillance system of antibiotic consumption in hospitals, in the community, and of resistance rates (RRs) in hospital settings. Data on antibiotic consumption and on antibiotic RRs have been collected from 2015 to 2017 from pharmacies and laboratories of participating hospitals and from community, respectively. Data on antibiotic consumption showed that the most consumed antibiotics in hospitals were fluoroquinolones in 2015, penicillin in 2016, and beta-lactams in 2017. From 2015 to 2017, data on Klebsiella pneumoniae showed significant increasing RRs to all antibiotic classes, except to carbapenems. RRs of third-generation cephalosporins and carbapenems Escherichia coli showed significant decreasing trends. RRs of the other microorganisms did not change significantly during the study period. The results from the present study show that in Sicily, the use of antibiotics and RRs for selected microorganisms are at a high level. Immediate strategies are needed to decrease the inappropriate usage of antibiotics and control the spread of AMR.

Suggested Citation

  • Martina Barchitta & Annalisa Quattrocchi & Andrea Maugeri & Maria Clara La Rosa & Claudia La Mastra & Laura Sessa & Pasquale Cananzi & Giuseppe Murolo & Alessandro Oteri & Guido Basile & Antonella Ago, 2019. "Antibiotic Consumption and Resistance during a 3-Year Period in Sicily, Southern Italy," IJERPH, MDPI, vol. 16(13), pages 1-10, June.
    • Handle: RePEc:gam:jijerp:v:16:y:2019:i:13:p:2253-:d:242970
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/16/13/2253/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/16/13/2253/
    Download Restriction: no
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Martina Barchitta & Annalisa Quattrocchi & Andrea Maugeri & Maria Clara La Rosa & Claudia La Mastra & Guido Basile & Giovanni Giuffrida & Francesco Mazzeo Rinaldi & Giuseppe Murolo & Antonella Agodi, 2020. "The “Obiettivo Antibiotico” Campaign on Prudent Use of Antibiotics in Sicily, Italy: The Pilot Phase," IJERPH, MDPI, vol. 17(9), pages 1-10, April.
    2. Elżbieta Rafa & Marta Z. Wałaszek & Michał J. Wałaszek & Adam Domański & Anna Różańska, 2021. "The Incidence of Healthcare-Associated Infections, Their Clinical Forms, and Microbiological Agents in Intensive Care Units in Southern Poland in a Multicentre Study from 2016 to 2019," IJERPH, MDPI, vol. 18(5), pages 1-12, February.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:16:y:2019:i:13:p:2253-:d:242970. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.