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Which Patients Are Prescribed Escitalopram?: Predictors for Escitalopram Prescriptions and Functional Outcomes among Patients with Acute Ischemic Stroke

Author

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  • Jarim Kim

    (School of Communication, Kookmin University, Bugak Hall 603, 77 Jeongneung-ro, Seongbuk-gu, Seoul 02707, Korea)

  • Yerim Kim

    (Department of Neurology, Kangdong Sacred Heart Hospital, College of Medicine, Hallym University, Seoul 05355, Korea
    College of Medicine, Seoul National University, Seoul 03080, Korea)

Abstract

Recent studies have demonstrated that antidepressants could enhance functional recovery via neuroplasticity beyond solely treating depression. However, since Koreans typically show a greater aversion to seeking psychiatric care than citizens of Western countries, the number of antidepressant prescriptions is low. Through this study, we aim to identify the factors that lead to the prescription of antidepressants in subjects with acute ischemic stroke (AIS) in clinical practice. A total of 775 patients with ischemic stroke (IS) participated in this study from March 2010 to May 2013. We used binary logistic regression to find predictors for escitalopram prescriptions. To reveal predictors for short-term functional outcomes, we used an adjusted regression model using a propensity score. Among the 775 participants, 39 (5.03%) were prescribed escitalopram. The duration of hospital stay (odds ratio (OR) = 1.07; 95% confidence interval (CI) = 1.04–1.10) and the use of mechanical ventilation were significantly more closely related to escitalopram prescriptions as compared to non-escitalopram prescriptions (OR = 5.15; 95% CI = 1.53–17.40). The use of escitalopram, on the other hand, was not significantly associated with short-term functional outcomes (OR = 1.27; 95% CI = 0.50–3.25). Duration of hospital stay and use of mechanical ventilation were significantly related to escitalopram prescriptions.

Suggested Citation

  • Jarim Kim & Yerim Kim, 2018. "Which Patients Are Prescribed Escitalopram?: Predictors for Escitalopram Prescriptions and Functional Outcomes among Patients with Acute Ischemic Stroke," IJERPH, MDPI, vol. 15(6), pages 1-10, May.
    • Handle: RePEc:gam:jijerp:v:15:y:2018:i:6:p:1085-:d:149269
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    References listed on IDEAS

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    1. Chandra S. Wijaya & Jovia J. Z. Lee & Syeda F. Husain & Cyrus S. H. Ho & Roger S. McIntyre & Wilson W. Tam & Roger C. M. Ho, 2018. "Differentiating Medicated Patients Suffering from Major Depressive Disorder from Healthy Controls by Spot Urine Measurement of Monoamines and Steroid Hormones," IJERPH, MDPI, vol. 15(5), pages 1-13, April.
    2. Yuncui Wang & Fen Yang & Hao Shi & Chongming Yang & Hui Hu, 2017. "What Type of Transitional Care Effectively Reduced Mortality and Improved ADL of Stroke Patients? A Meta-Analysis," IJERPH, MDPI, vol. 14(5), pages 1-16, May.
    3. He-Hong Geng & Xin-Wang Wang & Rong-Li Fu & Meng-Juan Jing & Ling-Ling Huang & Qing Zhang & Xiao-Xiao Wang & Pei-Xi Wang, 2016. "The Relationship between C-Reactive Protein Level and Discharge Outcome in Patients with Acute Ischemic Stroke," IJERPH, MDPI, vol. 13(7), pages 1-11, June.
    4. Adel A. Alhazzani & Ahmed A. Mahfouz & Ahmed Y. Abolyazid & Nabil J. Awadalla & Razia Aftab & Aesha Faraheen & Shamsun Nahar Khalil, 2018. "Study of Stroke Incidence in the Aseer Region, Southwestern Saudi Arabia," IJERPH, MDPI, vol. 15(2), pages 1-7, January.
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