IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v15y2018i6p1083-d149275.html
   My bibliography  Save this article

Alcoholism: A Multi-Systemic Cellular Insult to Organs

Author

Listed:
  • Ucee Dguzeh

    (Department of Physiology, New Jersey Medical School Rutgers, 185 S Orange Ave, Newark, NJ 07103, USA
    These authors contributed equally to this work.)

  • Natasha C. Haddad

    (Department of Physiology and Biophysics, College of Medicine, Howard University, 520 W Street, NW, #2309, Washington, DC 20059, USA
    These authors contributed equally to this work.)

  • Kathia T. S. Smith

    (Department of Physiology and Biophysics, College of Medicine, Howard University, 520 W Street, NW, #2309, Washington, DC 20059, USA
    These authors contributed equally to this work.)

  • John O. Johnson

    (Department of Physiology and Biophysics, College of Medicine, Howard University, 520 W Street, NW, #2309, Washington, DC 20059, USA)

  • Angelia A. Doye

    (Gwathmey Inc., Cambridge, MA 02138, USA)

  • Judith K. Gwathmey

    (Gwathmey Inc., Cambridge, MA 02138, USA
    School of Medicine, Boston University, Boston, MA 02215, USA)

  • Georges E. Haddad

    (Department of Physiology and Biophysics, College of Medicine, Howard University, 520 W Street, NW, #2309, Washington, DC 20059, USA)

Abstract

Alcohol abuse can affect more than the heart and the liver. Many observers often do not appreciate the complex and differing aspects of alcohol’s effects in pathophysiologies that have been reported in multiple organs. Chronic alcohol abuse is known to be associated with pathophysiological changes that often result in life-threatening clinical outcomes, e.g., breast and colon cancer, pancreatic disease, cirrhosis of the liver, diabetes, osteoporosis, arthritis, kidney disease, immune system dysfunction, hypertension, coronary artery disease, cardiomyopathy, and can be as far-reaching as to cause central nervous system disorders. In this review article, we will discuss the various organs impacted by alcohol abuse. The lack of clear guidelines on the amount and frequency of alcohol intake, complicated by personal demographics, make extrapolations to real-life practices at best difficult for public health policy-makers.

Suggested Citation

  • Ucee Dguzeh & Natasha C. Haddad & Kathia T. S. Smith & John O. Johnson & Angelia A. Doye & Judith K. Gwathmey & Georges E. Haddad, 2018. "Alcoholism: A Multi-Systemic Cellular Insult to Organs," IJERPH, MDPI, vol. 15(6), pages 1-12, May.
    • Handle: RePEc:gam:jijerp:v:15:y:2018:i:6:p:1083-:d:149275
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/15/6/1083/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/15/6/1083/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Yue Zhou & Jie Zheng & Sha Li & Tong Zhou & Pei Zhang & Hua-Bin Li, 2016. "Alcoholic Beverage Consumption and Chronic Diseases," IJERPH, MDPI, vol. 13(6), pages 1-27, May.
    2. Hae-Dong Jang & Jae-Young Hong & Kyungdo Han & Jae Chul Lee & Byung-Joon Shin & Sung-Woo Choi & Seung-Woo Suh & Jae-Hyuk Yang & Si-Young Park & Chungwon Bang, 2017. "Relationship between bone mineral density and alcohol intake: A nationwide health survey analysis of postmenopausal women," PLOS ONE, Public Library of Science, vol. 12(6), pages 1-11, June.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Donatello Carrino & Jacopo Junio Valerio Branca & Matteo Becatti & Ferdinando Paternostro & Gabriele Morucci & Massimo Gulisano & Lorenzo Di Cesare Mannelli & Alessandra Pacini, 2021. "Alcohol-Induced Blood-Brain Barrier Impairment: An In Vitro Study," IJERPH, MDPI, vol. 18(5), pages 1-14, March.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Dong Jun Sung & Harshvardhan Singh & Seung-Bum Oh & SoJung Kim, 2019. "Bone-Loading Physical Activity and Alcohol Intake but not BMI Affect Areal Bone Mineral Density in Young College-Aged Korean Women: A Cross-Sectional Study," IJERPH, MDPI, vol. 16(24), pages 1-10, December.
    2. Inhwan Lee & Jeonghyeon Kim & Hyunsik Kang, 2020. "Cardiorespiratory Fitness is Inversely Associated with Risk of Low Bone Mineral Density in Older Korean Men," IJERPH, MDPI, vol. 17(21), pages 1-10, October.
    3. Chin Yi Chan & Shaanthana Subramaniam & Norazlina Mohamed & Soelaiman Ima-Nirwana & Norliza Muhammad & Ahmad Fairus & Pei Yuen Ng & Nor Aini Jamil & Noorazah Abd Aziz & Kok-Yong Chin, 2020. "Determinants of Bone Health Status in a Multi-Ethnic Population in Klang Valley, Malaysia," IJERPH, MDPI, vol. 17(2), pages 1-16, January.
    4. Dávid Líška & Erika Liptáková & Miroslava Barcalová & Ľubomír Skladaný, 2024. "The impact of alcohol consumption on the quality of life of college students: a study from three Slovak universities," Palgrave Communications, Palgrave Macmillan, vol. 11(1), pages 1-8, December.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:15:y:2018:i:6:p:1083-:d:149275. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.