IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v14y2017i8p865-d106628.html
   My bibliography  Save this article

Increased Frequency of Rheumatoid Arthritis and Allergic Rhinitis among Pesticide Sprayers and Associations with Pesticide Use

Author

Listed:
  • Michalis Koureas

    (Department of Hygiene and Epidemiology, Faculty of Medicine, University of Thessaly, 22 Papakyriazi Street, 41222 Larissa, Greece)

  • George Rachiotis

    (Department of Hygiene and Epidemiology, Faculty of Medicine, University of Thessaly, 22 Papakyriazi Street, 41222 Larissa, Greece)

  • Andreas Tsakalof

    (Department of Hygiene and Epidemiology, Faculty of Medicine, University of Thessaly, 22 Papakyriazi Street, 41222 Larissa, Greece)

  • Christos Hadjichristodoulou

    (Department of Hygiene and Epidemiology, Faculty of Medicine, University of Thessaly, 22 Papakyriazi Street, 41222 Larissa, Greece)

Abstract

Objective : The aim of this study was to identify diseases linked with the pesticide sprayer occupation and explore possible associations with exposure history data. Methods : Α cross sectional study was conducted among pesticide sprayers ( n = 80) and the general population ( n = 90) in Thessaly (Greece). Medical history, demographic characteristics and detailed exposure history were recorded by conducting personal interviews. Lifetime exposure indicators were calculated for several pesticide chemical subclasses. Moreover, organophosphate metabolite levels were quantified in urine samples of all participants by using gas chromatography -mass spectrometry (GC-MS). Multinomial analysis was used to determine associations between occupational pesticide exposure and diseases or disorders. Results : In the pesticide sprayers group, significantly higher frequencies for rheumatoid arthritis (RA) and allergic rhinitis were observed compared with the control group ( p = 0.002 and p = 0.024 respectively). Within the pesticide sprayers group, high lifetime pesticide exposure was associated with increased risk for reporting RA (OR: 43.07 95% CI: 3.09–600.67) and allergic rhinitis (OR: 9.72 95% CI: 2.31–40.89), compared with low pesticide exposure. Exposure to organophsphate, guanidine and quinone pesticides were associated with RA while organophosphates, pyrethroids and paraquat were associated with allergic rhinitis. Despite the higher levels of certain pesticide metabolites observed among participants with rheumatoid arthritis, the differences were not statistically significant. One metabolite (diethylthiophosphate) was found to be significantly increased in allergic rhinitis cases ( p = 0.037). Conclusion s : The results from the current study suggest a possible association of occupational pesticide exposure with RA and allergic rhinitis that should be further investigated.

Suggested Citation

  • Michalis Koureas & George Rachiotis & Andreas Tsakalof & Christos Hadjichristodoulou, 2017. "Increased Frequency of Rheumatoid Arthritis and Allergic Rhinitis among Pesticide Sprayers and Associations with Pesticide Use," IJERPH, MDPI, vol. 14(8), pages 1-8, August.
    • Handle: RePEc:gam:jijerp:v:14:y:2017:i:8:p:865-:d:106628
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/14/8/865/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/14/8/865/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Wissem Mnif & Aziza Ibn Hadj Hassine & Aicha Bouaziz & Aghleb Bartegi & Olivier Thomas & Benoit Roig, 2011. "Effect of Endocrine Disruptor Pesticides: A Review," IJERPH, MDPI, vol. 8(6), pages 1-39, June.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Constantin C. Bungau & Codruta Bendea & Tudor Bungau & Andrei-Flavius Radu & Marcela Florina Prada & Ioana Francesca Hanga-Farcas & Cosmin Mihai Vesa, 2024. "The Relationship between the Parameters That Characterize a Built Living Space and the Health Status of Its Inhabitants," Sustainability, MDPI, vol. 16(5), pages 1-35, February.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Eva Matisová & Svetlana Hrouzková, 2012. "Analysis of Endocrine Disrupting Pesticides by Capillary GC with Mass Spectrometric Detection," IJERPH, MDPI, vol. 9(9), pages 1-31, September.
    2. Songhee Lee & Eun Ko & Hyojin Lee & Ki-Tae Kim & Moonsung Choi & Sooim Shin, 2021. "Mixed Exposure of Persistent Organic Pollutants Alters Oxidative Stress Markers and Mitochondrial Function in the Tail of Zebrafish Depending on Sex," IJERPH, MDPI, vol. 18(18), pages 1-13, September.
    3. Cliff Zinyemba & Emma Archer & Hanna-Andrea Rother, 2020. "Climate Change, Pesticides and Health: Considering the Risks and Opportunities of Adaptation for Zimbabwean Smallholder Cotton Growers," IJERPH, MDPI, vol. 18(1), pages 1-11, December.
    4. Ken Sexton & Jennifer J. Salinas & Thomas J. McDonald & Rose M. Z. Gowen & Rebecca P. Miller & Joseph B. McCormick & Susan P. Fisher-Hoch, 2013. "Biomarkers of Maternal and Fetal Exposure to Organochlorine Pesticides Measured in Pregnant Hispanic Women from Brownsville, Texas," IJERPH, MDPI, vol. 10(1), pages 1-12, January.
    5. Chao Zhang & Tiziana Schilirò & Marta Gea & Silvia Bianchi & Angelo Spinello & Alessandra Magistrato & Gianfranco Gilardi & Giovanna Di Nardo, 2020. "Molecular Basis for Endocrine Disruption by Pesticides Targeting Aromatase and Estrogen Receptor," IJERPH, MDPI, vol. 17(16), pages 1-18, August.
    6. René Viñas & Yow-Jiun Jeng & Cheryl S. Watson, 2012. "Non-Genomic Effects of Xenoestrogen Mixtures," IJERPH, MDPI, vol. 9(8), pages 1-21, July.
    7. Suphaphat Kwonpongsagoon & Chanokwan Katasila & Pornpimol Kongtip & Susan Woskie, 2021. "Application Intensity and Spatial Distribution of Three Major Herbicides from Agricultural and Nonagricultural Practices in the Central Plain of Thailand," IJERPH, MDPI, vol. 18(6), pages 1-19, March.
    8. Pornpimol Kongtip & Noppanun Nankongnab & Mathuros Tipayamongkholgul & Ariya Bunngamchairat & Jutharak Yimsabai & Aranya Pataitiemthong & Susan Woskie, 2018. "A Cross-Sectional Investigation of Cardiovascular and Metabolic Biomarkers among Conventional and Organic Farmers in Thailand," IJERPH, MDPI, vol. 15(11), pages 1-12, November.
    9. Marta Gea & Chao Zhang & Roberta Tota & Gianfranco Gilardi & Giovanna Di Nardo & Tiziana Schilirò, 2022. "Assessment of Five Pesticides as Endocrine-Disrupting Chemicals: Effects on Estrogen Receptors and Aromatase," IJERPH, MDPI, vol. 19(4), pages 1-10, February.
    10. Muyesaier Tudi & Huada Daniel Ruan & Li Wang & Jia Lyu & Ross Sadler & Des Connell & Cordia Chu & Dung Tri Phung, 2021. "Agriculture Development, Pesticide Application and Its Impact on the Environment," IJERPH, MDPI, vol. 18(3), pages 1-23, January.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:14:y:2017:i:8:p:865-:d:106628. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.