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The Prevalence of Hypertension Accompanied by High Homocysteine and its Risk Factors in a Rural Population: A Cross-Sectional Study from Northeast China

Author

Listed:
  • Ye Chang

    (Department of Cardiology, the First Hospital of China Medical University, Shenyang 110001, China)

  • Yuan Li

    (Department of Cardiology, the First Hospital of China Medical University, Shenyang 110001, China)

  • Xiaofan Guo

    (Department of Cardiology, the First Hospital of China Medical University, Shenyang 110001, China)

  • Yintao Chen

    (Department of Cardiology, the First Hospital of China Medical University, Shenyang 110001, China)

  • Dongxue Dai

    (Department of Cardiology, the First Hospital of China Medical University, Shenyang 110001, China)

  • Yingxian Sun

    (Department of Cardiology, the First Hospital of China Medical University, Shenyang 110001, China)

Abstract

Previous studies found that hypertension and high homocysteine (HHcy) exhibited a synergistic effect on the risk of cardiovascular diseases. This study aimed to investigate the prevalence of hypertension accompanied by HHcy and its risk factors in the rural areas of northeast China. This study was conducted using a stratified cluster random sampling method, and included 6529 subjects with complete data. Demographic characteristics were obtained from a questionnaire. Blood pressure and anthropometric indices were measured, and serum indices were analyzed. Hypertension accompanied by HHcy was defined as hypertension plus HHcy [homocysteine (Hcy) > 10 µmol/L]. The mean concentration of Hcy was 17.29 μmol/L in the general population. The prevalence of hypertension accompanied by HHcy was so high that it reached 45.1% of our study population and accounted for 86.8% of the total participants with hypertension. Multiple logistic regression analysis indicated that the modifiable risk factors of hypertension accompanied by HHcy included obesity, diabetes, dyslipidemia, and inactive physical activities. We found that the mean level of Hcy, and the prevalences of HHcy and hypertension accompanied by HHcy were very high among the rural population of northeast China. Obesity, diabetes, dyslipidemia, and inactive physical activities were modifiable risk factors of hypertension accompanied by HHcy.

Suggested Citation

  • Ye Chang & Yuan Li & Xiaofan Guo & Yintao Chen & Dongxue Dai & Yingxian Sun, 2017. "The Prevalence of Hypertension Accompanied by High Homocysteine and its Risk Factors in a Rural Population: A Cross-Sectional Study from Northeast China," IJERPH, MDPI, vol. 14(4), pages 1-16, April.
    • Handle: RePEc:gam:jijerp:v:14:y:2017:i:4:p:376-:d:94865
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    References listed on IDEAS

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    1. Qing Zhang & De-Xing Qiu & Rong-Li Fu & Tian-Fen Xu & Meng-Juan Jing & Hui-Shan Zhang & He-Hong Geng & Long-Chao Zheng & Pei-Xi Wang, 2016. "H-Type Hypertension and C Reactive Protein in Recurrence of Ischemic Stroke," IJERPH, MDPI, vol. 13(5), pages 1-9, May.
    2. Shuxia Guo & Hongrui Pang & Heng Guo & Mei Zhang & Jia He & Yizhong Yan & Qiang Niu & Muratbek & Dongsheng Rui & Shugang Li & Rulin Ma & Jingyu Zhang & Jiaming Liu & Yusong Ding, 2015. "Ethnic Differences in the Prevalence of High Homocysteine Levels Among Low-Income Rural Kazakh and Uyghur Adults in Far Western China and Its Implications for Preventive Public Health," IJERPH, MDPI, vol. 12(5), pages 1-13, May.
    3. Ye Chang & Yuan Li & Xiaofan Guo & Dongxue Dai & Yingxian Sun, 2016. "The Association of Ideal Cardiovascular Health and Atherogenic Index of Plasma in Rural Population: A Cross-Sectional Study from Northeast China," IJERPH, MDPI, vol. 13(10), pages 1-13, October.
    4. Liang Guo & Xiaofan Guo & Ye Chang & Zhao Li & Shasha Yu & Hongmei Yang & Yingxian Sun, 2016. "Modified Ideal Cardiovascular Health Status is Associated with Lower Prevalence of Stroke in Rural Northeast China," IJERPH, MDPI, vol. 13(2), pages 1-10, February.
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    Cited by:

    1. Andong Ji & Chunlei Pan & Hongxia Wang & Zhezhen Jin & Joseph H. Lee & Qincheng Wu & Qixiao Jiang & Lianhua Cui, 2019. "Prevalence and Associated Risk Factors of Chronic Kidney Disease in an Elderly Population from Eastern China," IJERPH, MDPI, vol. 16(22), pages 1-15, November.

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