IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v13y2016i6p532-d70797.html
   My bibliography  Save this article

Comments on Li et al . Effects of in Utero Exposure to Dicyclohexyl Phthalate on Rat Fetal Leydig Cells. Int. J. Environ. Res. Public Health 2016, 13 , 246

Author

Listed:
  • Terje Svingen

    (Division of Diet, Disease Prevention and Toxicology, National Food Institute, Technical University of Denmark, Søborg DK-2860, Denmark)

Abstract

Profiling the expression levels of genes or proteins in tissues comprising two or more cell types is commonplace in biological sciences. Such analyses present particular challenges, however, for example a potential shift in cellular composition, or ‘cellularity’, between specimens. That is, does an observed change in expression level represent what occurs within individual cells, or does it represent a shift in the ratio of different cell types within the tissue? This commentary attempts to highlight the importance of considering cellularity when interpreting quantitative expression data, using the mammalian testis and a recent study on the effects of phthalate exposure on testis function as an example.

Suggested Citation

  • Terje Svingen, 2016. "Comments on Li et al . Effects of in Utero Exposure to Dicyclohexyl Phthalate on Rat Fetal Leydig Cells. Int. J. Environ. Res. Public Health 2016, 13 , 246," IJERPH, MDPI, vol. 13(6), pages 1-3, May.
    • Handle: RePEc:gam:jijerp:v:13:y:2016:i:6:p:532-:d:70797
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/13/6/532/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/13/6/532/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Xiaoheng Li & Xiaomin Chen & Guoxin Hu & Linxi Li & Huina Su & Yiyan Wang & Dongxin Chen & Qiqi Zhu & Chao Li & Junwei Li & Mingcang Wang & Qingquan Lian & Ren-Shan Ge, 2016. "Effects of in Utero Exposure to Dicyclohexyl Phthalate on Rat Fetal Leydig Cells," IJERPH, MDPI, vol. 13(3), pages 1-12, February.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Henrieta Hlisníková & Ida Petrovičová & Branislav Kolena & Miroslava Šidlovská & Alexander Sirotkin, 2020. "Effects and Mechanisms of Phthalates’ Action on Reproductive Processes and Reproductive Health: A Literature Review," IJERPH, MDPI, vol. 17(18), pages 1-37, September.
    2. Wanglong Zheng & Wentong Fan & Nannan Feng & Nanyan Lu & Hui Zou & Jianhong Gu & Yan Yuan & Xuezhong Liu & Jianfa Bai & Jianchun Bian & Zongping Liu, 2019. "The Role of miRNAs in Zearalenone-Promotion of TM3 Cell Proliferation," IJERPH, MDPI, vol. 16(9), pages 1-19, April.

    More about this item

    Keywords

    n/a;

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:13:y:2016:i:6:p:532-:d:70797. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.