IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v13y2016i2p181-d63267.html
   My bibliography  Save this article

Environmental Chemical Assessment in Clinical Practice: Unveiling the Elephant in the Room

Author

Listed:
  • Nicole Bijlsma

    (School of Health Sciences, RMIT University, Bundoora, Victoria 3083, Australia
    These authors contributed equally to this work.)

  • Marc M. Cohen

    (School of Health Sciences, RMIT University, Bundoora, Victoria 3083, Australia
    These authors contributed equally to this work.)

Abstract

A growing body of evidence suggests chemicals present in air, water, soil, food, building materials and household products are toxicants that contribute to the many chronic diseases typically seen in routine medical practice. Yet, despite calls from numerous organisations to provide clinicians with more training and awareness in environmental health, there are multiple barriers to the clinical assessment of toxic environmental exposures. Recent developments in the fields of systems biology, innovative breakthroughs in biomedical research encompassing the “-omics” fields, and advances in mobile sensing, peer-to-peer networks and big data, provide tools that future clinicians can use to assess environmental chemical exposures in their patients. There is also a need for concerted action at all levels, including actions by individual patients, clinicians, medical educators, regulators, government and non-government organisations, corporations and the wider civil society, to understand the “exposome” and minimise the extent of toxic exposures on current and future generations. Clinical environmental chemical risk assessment may provide a bridge between multiple disciplines that uses new technologies to herald in a new era in personalised medicine that unites clinicians, patients and civil society in the quest to understand and master the links between the environment and human health.

Suggested Citation

  • Nicole Bijlsma & Marc M. Cohen, 2016. "Environmental Chemical Assessment in Clinical Practice: Unveiling the Elephant in the Room," IJERPH, MDPI, vol. 13(2), pages 1-27, February.
  • Handle: RePEc:gam:jijerp:v:13:y:2016:i:2:p:181-:d:63267
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/13/2/181/pdf
    Download Restriction: no

    File URL: https://www.mdpi.com/1660-4601/13/2/181/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Vanessa Delfosse & Béatrice Dendele & Tiphaine Huet & Marina Grimaldi & Abdelhay Boulahtouf & Sabine Gerbal-Chaloin & Bertrand Beucher & Dominique Roecklin & Christina Muller & Roger Rahmani & Vincent, 2015. "Synergistic activation of human pregnane X receptor by binary cocktails of pharmaceutical and environmental compounds," Nature Communications, Nature, vol. 6(1), pages 1-10, November.
    2. Andrew V. Biankin & Steven Piantadosi & Simon J. Hollingsworth, 2015. "Patient-centric trials for therapeutic development in precision oncology," Nature, Nature, vol. 526(7573), pages 361-370, October.
    3. John A. Hird, 1993. "Environmental policy and equity: The case of superfund," Journal of Policy Analysis and Management, John Wiley & Sons, Ltd., vol. 12(2), pages 323-343.
    4. Gomez, S.L. & Quach, T. & Horn-Ross, P.L. & Pham, J.T. & Cockburn, M. & Chang, E.T. & Keegan, T.H.M. & Glaser, S.L. & Clarke, C.A., 2010. "Hidden breast cancer disparities in asian women: Disaggregating incidence rates by ethnicity and migrant status," American Journal of Public Health, American Public Health Association, vol. 100(S1), pages 125-131.
    5. Yuwadee Ngamwong & Wimonchat Tangamornsuksan & Ornrat Lohitnavy & Nathorn Chaiyakunapruk & C Norman Scholfield & Brad Reisfeld & Manupat Lohitnavy, 2015. "Additive Synergism between Asbestos and Smoking in Lung Cancer Risk: A Systematic Review and Meta-Analysis," PLOS ONE, Public Library of Science, vol. 10(8), pages 1-19, August.
    6. T. Andrew Clayton & John C. Lindon & Olivier Cloarec & Henrik Antti & Claude Charuel & Gilles Hanton & Jean-Pierre Provost & Jean-Loïc Le Net & David Baker & Rosalind J. Walley & Jeremy R. Everett & J, 2006. "Pharmaco-metabonomic phenotyping and personalized drug treatment," Nature, Nature, vol. 440(7087), pages 1073-1077, April.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Ryan Johnson & Kim Ramsey-White & Christina H. Fuller, 2016. "Socio-demographic Differences in Toxic Release Inventory Siting and Emissions in Metro Atlanta," IJERPH, MDPI, vol. 13(8), pages 1-12, July.
    2. María Elena Martínez & Jonathan T Unkart & Li Tao & Candyce H Kroenke & Richard Schwab & Ian Komenaka & Scarlett Lin Gomez, 2017. "Prognostic significance of marital status in breast cancer survival: A population-based study," PLOS ONE, Public Library of Science, vol. 12(5), pages 1-14, May.
    3. Efren Garcia-Maldonado & Andrew D. Huber & Sergio C. Chai & Stanley Nithianantham & Yongtao Li & Jing Wu & Shyaron Poudel & Darcie J. Miller & Jayaraman Seetharaman & Taosheng Chen, 2024. "Chemical manipulation of an activation/inhibition switch in the nuclear receptor PXR," Nature Communications, Nature, vol. 15(1), pages 1-14, December.
    4. Rae Zimmerman, 1993. "Social Equity and Environmental Risk," Risk Analysis, John Wiley & Sons, vol. 13(6), pages 649-666, December.
    5. Hanafi, Mohamed & Ouertani, Samia Samar & Boccard, Julien & Mazerolles, Gérard & Rudaz, Serge, 2015. "Multi-way PLS regression: Monotony convergence of tri-linear PLS2 and optimality of parameters," Computational Statistics & Data Analysis, Elsevier, vol. 83(C), pages 129-139.
    6. Cory, Dennis C. & Rahman, Tauhidur, 2009. "Environmental justice and enforcement of the safe drinking water act: The Arizona arsenic experience," Ecological Economics, Elsevier, vol. 68(6), pages 1825-1837, April.
    7. Michael Greenstone & Justin Gallagher, 2008. "Does Hazardous Waste Matter? Evidence from the Housing Market and the Superfund Program," The Quarterly Journal of Economics, President and Fellows of Harvard College, vol. 123(3), pages 951-1003.
    8. Anna Suraya & Dennis Nowak & Astrid Widajati Sulistomo & Aziza Ghanie Icksan & Elisna Syahruddin & Ursula Berger & Stephan Bose-O’Reilly, 2020. "Asbestos-Related Lung Cancer: A Hospital-Based Case-Control Study in Indonesia," IJERPH, MDPI, vol. 17(2), pages 1-10, January.
    9. Andrew B. Whitford, 2007. "Competing Explanations for Bureaucratic Preferences," Journal of Theoretical Politics, , vol. 19(3), pages 219-247, July.
    10. Shinji Fukuda & Yumiko Nakanishi & Eisuke Chikayama & Hiroshi Ohno & Tsuneo Hino & Jun Kikuchi, 2009. "Evaluation and Characterization of Bacterial Metabolic Dynamics with a Novel Profiling Technique, Real-Time Metabolotyping," PLOS ONE, Public Library of Science, vol. 4(3), pages 1-10, March.
    11. William M. Bowen, 1999. "Comments on “‘Every Breath You Take... ’: The Demographics of Toxic Air Releases in Southern Californiaâ€," Economic Development Quarterly, , vol. 13(2), pages 124-134, May.
    12. Sonja Klebe & James Leigh & Douglas W. Henderson & Markku Nurminen, 2019. "Asbestos, Smoking and Lung Cancer: An Update," IJERPH, MDPI, vol. 17(1), pages 1-23, December.
    13. Lucia Fazzo & Alessandra Binazzi & Daniela Ferrante & Giada Minelli & Dario Consonni & Lisa Bauleo & Caterina Bruno & Marcella Bugani & Marco De Santis & Ivano Iavarone & Corrado Magnani & Elisa Romeo, 2021. "Burden of Mortality from Asbestos-Related Diseases in Italy," IJERPH, MDPI, vol. 18(19), pages 1-14, September.
    14. Ran An & Peng Liu, 2023. "Research on the Environmental Philosophy of China’s Environmental Crime Legislation from the Perspective of Ecological Civilization Construction," IJERPH, MDPI, vol. 20(2), pages 1-19, January.
    15. Revesz, Richard & Stavins, Robert, 2004. "Environmental Law and Policy," Working Paper Series rwp04-023, Harvard University, John F. Kennedy School of Government.
    16. Kniesner, Thomas J. & Viscusi, W. Kip, 2023. "Promoting Equity through Equitable Risk Tradeoffs," Journal of Benefit-Cost Analysis, Cambridge University Press, vol. 14(1), pages 8-34, March.
    17. Jiabao Liu & Ainaz Malekoltojari & Anjana Asokakumar & Vimanda Chow & Linhao Li & Hao Li & Marina Grimaldi & Nathanlown Dang & Jhenielle Campbell & Holly Barrett & Jianxian Sun & William Navarre & Der, 2024. "Diindoles produced from commensal microbiota metabolites function as endogenous CAR/Nr1i3 ligands," Nature Communications, Nature, vol. 15(1), pages 1-12, December.
    18. Fischhendler, Itay, 2007. "Escaping the "polluter pays" trap: Financing wastewater treatment on the Tijuana-San Diego border," Ecological Economics, Elsevier, vol. 63(2-3), pages 485-498, August.
    19. Susan L. Cutter & Danika Holm & Lloyd Clark, 1996. "The Role of Geographic Scale in Monitoring Environmental Justice," Risk Analysis, John Wiley & Sons, vol. 16(4), pages 517-526, August.
    20. Andrew B. Whitford, 2008. "A Test of the Political Control of Bureaucracies Under Asymmetric Information," Rationality and Society, , vol. 20(4), pages 445-470, November.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:13:y:2016:i:2:p:181-:d:63267. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.