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Effect of Pesticide Exposure on Immunological, Hematological and Biochemical Parameters in Thai Orchid Farmers— A Cross-Sectional Study

Author

Listed:
  • Soraya Aroonvilairat

    (Center of Excellence on Environmental Health and Toxicology (EHT), and Laboratory of Immunology, Kampangpetch 6 Road, Lak-si, Bangkok 10210, Thailand)

  • Wannapa Kespichayawattana

    (Center of Excellence on Environmental Health and Toxicology (EHT), and Laboratory of Immunology, Kampangpetch 6 Road, Lak-si, Bangkok 10210, Thailand)

  • Thiwaree Sornprachum

    (Center of Excellence on Environmental Health and Toxicology (EHT), and Laboratory of Immunology, Kampangpetch 6 Road, Lak-si, Bangkok 10210, Thailand)

  • Papada Chaisuriya

    (Center of Excellence on Environmental Health and Toxicology (EHT), and Laboratory of Immunology, Kampangpetch 6 Road, Lak-si, Bangkok 10210, Thailand)

  • Taweeratana Siwadune

    (Department of Mathematics, Faculty of Science, Mahidol University, Rama VI Road, Ratchathewi, Bangkok 10400, Thailand)

  • Kavi Ratanabanangkoon

    (Center of Excellence on Environmental Health and Toxicology (EHT), and Laboratory of Immunology, Kampangpetch 6 Road, Lak-si, Bangkok 10210, Thailand
    Chulabhorn Graduate Institute, Kampangpetch 6 Road, Lak-si, Bangkok 10210, Thailand)

Abstract

Various studies have found that many Thai orchid farmers used excessive amounts of pesticides without proper protective gear, but no toxicological study has been made. This cross-sectional study aimed to evaluate the immunological, hematological and biochemical statuses of these farmers. Sixty four orchid farmers and 60 controls were studied. Plasma cholinesterase activity, the percentage and absolute number of B lymphocytes (CD19 + ) were significantly lower in the farmers group (3966.32 ± 1165.48 U/L, 11.61 ± 4.09% and 312.26 ± 164.83 cells/mm3, respectively) as compared to those of controls (5048.85 ± 1139.40 U/L, 14.32 ± 4.23%, 420.34 ± 195.18 cells/mm 3 , respectively). There was a statistically significant higher level of serum IgE among the orchid farmers (0.031 ± 0.011 mg/dL vs. 0.018 ± 0.007 mg/dL) but not IgG, IgA and IgM, levels. Serum lysozyme level, lymphocyte proliferative responses to mitogens, hematological parameters and kidney function test, were not significantly different between the two groups. The liver function profiles showed significantly lower levels of albumin and serum protein in the farmer group. Thus frequent pesticide exposure resulted in subtle changes of some biological parameters. These changes, though may not be clinically significant, strongly indicated that caution in handing pesticides by these farmers is warranted.

Suggested Citation

  • Soraya Aroonvilairat & Wannapa Kespichayawattana & Thiwaree Sornprachum & Papada Chaisuriya & Taweeratana Siwadune & Kavi Ratanabanangkoon, 2015. "Effect of Pesticide Exposure on Immunological, Hematological and Biochemical Parameters in Thai Orchid Farmers— A Cross-Sectional Study," IJERPH, MDPI, vol. 12(6), pages 1-16, May.
    • Handle: RePEc:gam:jijerp:v:12:y:2015:i:6:p:5846-5861:d:50210
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    Cited by:

    1. Neeranuch Suwannarin & Tippawan Prapamontol & Tomohiko Isobe & Yukiko Nishihama & Ampica Mangklabruks & Tawiwan Pantasri & Somporn Chantara & Warangkana Naksen & Shoji F. Nakayama, 2021. "Association between Haematological Parameters and Exposure to a Mixture of Organophosphate and Neonicotinoid Insecticides among Male Farmworkers in Northern Thailand," IJERPH, MDPI, vol. 18(20), pages 1-14, October.

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