IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v10y2013i9p3987-3997d28438.html
   My bibliography  Save this article

Association between Metabolic Syndrome and Chronic Kidney Disease in Perimenopausal Women

Author

Listed:
  • Yongqiang Li

    (Department of Nephronology, Institute of Nephronology and Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China
    These authors contributed equally to this work.)

  • Liqin Zhao

    (The Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China
    These authors contributed equally to this work.)

  • Youming Chen

    (Clinical laboratory, the Third Affiliated Hospital of Southern, Medical University, Guangzhou 510630, China)

  • Aiqun Liu

    (Department of Nephronology, Institute of Nephronology and Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China)

  • Xinyu Liu

    (Department of Nephronology, Institute of Nephronology and Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China)

  • Xiaofei Shao

    (Department of Nephronology, Institute of Nephronology and Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China)

  • Ying Zhang

    (Department of Nephronology, Institute of Nephronology and Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China)

  • Honglei Wang

    (Department of Nephronology, Institute of Nephronology and Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China)

  • Xiaohong Wang

    (Department of Nephronology, Institute of Nephronology and Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China)

  • Bin Li

    (Department of Nephronology, Institute of Nephronology and Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China)

  • Kangping Deng

    (Department of Nephronology, Institute of Nephronology and Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China)

  • Qin Liu

    (Department of Nephronology, Institute of Nephronology and Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China)

  • Harry Holthöfer

    (National Centre for Sensor Research/BioAnalytical Sciences, Dublin City University, Dublin 9, Ireland)

  • Hequn Zou

    (Department of Nephronology, Institute of Nephronology and Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China)

Abstract

The purpose of the study was to explore the association between metabolic syndrome (MetS) and chronic kidney disease (CKD) in perimenopausal women. A cross-sectional study was conducted in Zhuhai from June to October 2012. Perimenopausal women (n = 685) were included in the study. All participants were divided into three subgroups: Group 1, 40 years old ≤ Age < 50 years old; Group 2, 50 years old ≤ Age < 60 years old; Group 3, 60 years old ≤ Age ≤ 65 years old. MetS was associated with CKD ( p < 0.01) in the unadjusted analyses in total subjects. After adjusting the potential confounders, the odd ratios of CKD for MetS was 2.66 (95% CI 1.56 to 4.49, p < 0.001). There was no relationship between MetS and CKD in both Group 1 and Group 3. MetS was associated with CKD ( p < 0.001) in the unadjusted analyses in Group 2. After adjusting for potential confounders, MetS was significantly associated with CKD. The odd ratios for MetS was 6.79 (95% CI 2.30 to 20.09, p < 0.001). There was no relationship between elevated blood pressure, elevated fasting glucose, abdominal obesity, Low HDL cholesterol, elevated triglycerides and CKD in both Group 1 and Group 3. Elevated blood pressure was associated with CKD in Group 2 (unadjusted Odds ratio: 4.52 (1.28–16.02), p = 0.02). After adjusting for potential confounders, there was no relationship between elevated blood pressure and CKD ( p = 0.78). Elevated fasting glucose was associated with CKD in Group 2 (unadjusted Odds ratio: 3.69 (1.10–12.38), p = 0.03). After adjusting for potential confounders, there was no relationship between elevated fasting glucose and CKD ( p = 0.15). There was no relationship between abdominal obesity, Low HDL cholesterol, elevated triglycerides and CKD in Group 2. These findings suggest that in perimenopausal women aged from 50 or older to 60 MetS was associated with CKD. There is no relationship between MetS and CKD in perimenopausal women aged from 40 or older to 50 and aged from 60 or older to 65.

Suggested Citation

  • Yongqiang Li & Liqin Zhao & Youming Chen & Aiqun Liu & Xinyu Liu & Xiaofei Shao & Ying Zhang & Honglei Wang & Xiaohong Wang & Bin Li & Kangping Deng & Qin Liu & Harry Holthöfer & Hequn Zou, 2013. "Association between Metabolic Syndrome and Chronic Kidney Disease in Perimenopausal Women," IJERPH, MDPI, vol. 10(9), pages 1-11, August.
    • Handle: RePEc:gam:jijerp:v:10:y:2013:i:9:p:3987-3997:d:28438
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/10/9/3987/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/10/9/3987/
    Download Restriction: no
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Yongqiang Li & Shanying Chen & Xiaofei Shao & Jia Guo & Xinyu Liu & Aiqun Liu & Ying Zhang & Honglei Wang & Bin Li & Kangping Deng & Qin Liu & Harry Holthöfer & Hequn Zou, 2014. "Association of Uric Acid with Metabolic Syndrome in Men, Premenopausal Women and Postmenopausal Women," IJERPH, MDPI, vol. 11(3), pages 1-12, March.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:10:y:2013:i:9:p:3987-3997:d:28438. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.