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Lithium in Tap Water and Suicide Mortality in Japan

Author

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  • Norio Sugawara

    (Department of Neuropsychiatry, Hirosaki University School of Medicine, 5 Zaifucho, Hirosaki, Aomori 036-8562, Japan)

  • Norio Yasui-Furukori

    (Department of Neuropsychiatry, Hirosaki University School of Medicine, 5 Zaifucho, Hirosaki, Aomori 036-8562, Japan)

  • Nobuyoshi Ishii

    (Department of Neuropsychiatry, Oita University Faculty of Medicine, Idaigaoka 1-1, Hasama-machi, Yufu, Oita 879-5593, Japan)

  • Noboru Iwata

    (Department of Clinical Psychology, Hiroshima International University, 555-36 Kurose-Gakuendai, Higashi-Hiroshima, Hiroshima 739-2695, Japan)

  • Takeshi Terao

    (Department of Neuropsychiatry, Oita University Faculty of Medicine, Idaigaoka 1-1, Hasama-machi, Yufu, Oita 879-5593, Japan)

Abstract

Lithium has been used as a mood-stabilizing drug in people with mood disorders. Previous studies have shown that natural levels of lithium in drinking water may protect against suicide. This study evaluated the association between lithium levels in tap water and the suicide standardized mortality ratio (SMR) in 40 municipalities of Aomori prefecture, which has the highest levels of suicide mortality rate in Japan. Lithium levels in the tap water supplies of each municipality were measured using inductively coupled plasma-mass spectrometry. After adjusting for confounders, a statistical trend toward significance was found for the relationship between lithium levels and the average SMR among females. These findings indicate that natural levels of lithium in drinking water might have a protective effect on the risk of suicide among females. Future research is warranted to confirm this association.

Suggested Citation

  • Norio Sugawara & Norio Yasui-Furukori & Nobuyoshi Ishii & Noboru Iwata & Takeshi Terao, 2013. "Lithium in Tap Water and Suicide Mortality in Japan," IJERPH, MDPI, vol. 10(11), pages 1-5, November.
  • Handle: RePEc:gam:jijerp:v:10:y:2013:i:11:p:6044-6048:d:30350
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    References listed on IDEAS

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    1. Jane E. Baird & Robert C. Zelin II & Dale E. Marxen, 1998. "Gender Differences in the Job Attitudes of Accountants," American Journal of Business, Emerald Group Publishing, vol. 13(2), pages 35-44.
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    Cited by:

    1. Nikoline N. Knudsen & Jörg Schullehner & Birgitte Hansen & Lisbeth F. Jørgensen & Søren M. Kristiansen & Denitza D. Voutchkova & Thomas A. Gerds & Per K. Andersen & Kristine Bihrmann & Morten Grønbæk , 2017. "Lithium in Drinking Water and Incidence of Suicide: A Nationwide Individual-Level Cohort Study with 22 Years of Follow-Up," IJERPH, MDPI, vol. 14(6), pages 1-13, June.

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    Keywords

    lithium; suicide rate; Japan;
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