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Converting clinical risks into economic value: The role of expectations and institutions in health technology development

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  • Lehoux, P.
  • Miller, F.A.
  • Daudelin, G.

Abstract

The ability to handle clinical and business risks is critical to an academic spin-off that seeks to develop a new medical technology. The milestones it has to meet to materialize its innovation are objects of speculation for those who finance its operations, and also for stakeholders who comment publicly on its progress. Such future-oriented expectations are not, however, mere hype since they operate within a set of practices that are highly institutionalized. Building on insights from sociology of expectations and institutions, this paper elicits how specific institutional requirements provide potency to the expectations that pave the health technology development pathway. Nested within five years of qualitative fieldwork, our study relies on a media coverage analysis to examine, over a decade, technology development in five Canadian spin-offs. Our findings illustrate a three-step process that involves: 1) measuring clinical risks that are convertible into business opportunities; 2) structuring technological entrepreneurship for growth; and 3) mitigating commercial risks to protect the spin-offs' economic value. Over time, expectations and institutions redefine where risks and opportunities lie, converting clinical risks into economic value. While the spin-offs support speculative economic value extraction, the technologies they materialize may fall short of fulfilling their clinical promises.

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  • Lehoux, P. & Miller, F.A. & Daudelin, G., 2017. "Converting clinical risks into economic value: The role of expectations and institutions in health technology development," Technological Forecasting and Social Change, Elsevier, vol. 117(C), pages 206-216.
    • Handle: RePEc:eee:tefoso:v:117:y:2017:i:c:p:206-216
    DOI: 10.1016/j.techfore.2016.11.026
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    References listed on IDEAS

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    1. Vohora, Ajay & Wright, Mike & Lockett, Andy, 2004. "Critical junctures in the development of university high-tech spinout companies," Research Policy, Elsevier, vol. 33(1), pages 147-175, January.
    2. Ben R. Martin, 2016. "Twenty challenges for innovation studies," Science and Public Policy, Oxford University Press, vol. 43(3), pages 432-450.
    3. Lazonick, William & Tulum, Öner, 2011. "US biopharmaceutical finance and the sustainability of the biotech business model," Research Policy, Elsevier, vol. 40(9), pages 1170-1187.
    4. Lehoux, P. & Daudelin, G. & Williams-Jones, B. & Denis, J.-L. & Longo, C., 2014. "How do business model and health technology design influence each other? Insights from a longitudinal case study of three academic spin-offs," Research Policy, Elsevier, vol. 43(6), pages 1025-1038.
    5. Paul Nightingale & Alex Coad, 2014. "Muppets and gazelles: political and methodological biases in entrepreneurship research," Industrial and Corporate Change, Oxford University Press and the Associazione ICC, vol. 23(1), pages 113-143, February.
    6. Rosengarten, Marsha & Michael, Mike, 2009. "The performative function of expectations in translating treatment to prevention: The case of HIV pre-exposure prophylaxis, or PrEP," Social Science & Medicine, Elsevier, vol. 69(7), pages 1049-1055, October.
    7. Antoaneta P. Petkova & Violina P. Rindova & Anil K. Gupta, 2013. "No News Is Bad News: Sensegiving Activities, Media Attention, and Venture Capital Funding of New Technology Organizations," Organization Science, INFORMS, vol. 24(3), pages 865-888, June.
    8. Geels, Frank W., 2004. "From sectoral systems of innovation to socio-technical systems: Insights about dynamics and change from sociology and institutional theory," Research Policy, Elsevier, vol. 33(6-7), pages 897-920, September.
    9. Guice, Jon, 1999. "Designing the future: the culture of new trends in science and technology," Research Policy, Elsevier, vol. 28(1), pages 81-98, January.
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    Cited by:

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    4. Erzurumlu, S. Sinan & Pachamanova, Dessislava, 2020. "Topic modeling and technology forecasting for assessing the commercial viability of healthcare innovations," Technological Forecasting and Social Change, Elsevier, vol. 156(C).
    5. Susan K. Sell, 2021. "21st Century Capitalism and Innovation for Health," Global Policy, London School of Economics and Political Science, vol. 12(S6), pages 12-20, July.
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