IDEAS home Printed from https://ideas.repec.org/a/eee/socmed/v68y2009i6p1069-1074.html
   My bibliography  Save this article

Barriers to clinical research participation in a diabetes randomized clinical trial

Author

Listed:
  • Robiner, William N.
  • Yozwiak, John A.
  • Bearman, Diane L.
  • Strand, Trudy D.
  • Strasburg, Katherine R.

Abstract

Little is known about how barriers to research participation are perceived, affected by or interact with patient characteristics, or how they vary over the course of a clinical trial. Participants (285) in the Renin-Angiotensin System Study (RASS), a randomized clinical primary prevention study of diabetic nephropathy and retinopathy at 2 Canadian and 1 US university, rated potential barriers to research participation yearly for 5 years. Baseline barriers rated as most adversely affecting participation were: missing work; frequency of appointments and procedures; study length; number of appointments and procedures; access to study location; and physical discomfort associated with procedures. Inadequate social support, unstable job, and the use of alcohol and drugs were cited relatively infrequently, suggesting that although they may be important, candidates for whom these might be issues likely self-selected out of the study. Gender and gender by age interactions were found for specific perceived barriers, such as work and child care, and baseline barriers correlated with adherence. Elucidating the natural history of barriers to research participation is a step toward identifying strategies for helping participants overcome them, and ultimately may enhance the conduct of research.

Suggested Citation

  • Robiner, William N. & Yozwiak, John A. & Bearman, Diane L. & Strand, Trudy D. & Strasburg, Katherine R., 2009. "Barriers to clinical research participation in a diabetes randomized clinical trial," Social Science & Medicine, Elsevier, vol. 68(6), pages 1069-1074, March.
    • Handle: RePEc:eee:socmed:v:68:y:2009:i:6:p:1069-1074
    as

    Download full text from publisher

    File URL: http://www.sciencedirect.com/science/article/pii/S0277-9536(08)00669-2
    Download Restriction: Full text for ScienceDirect subscribers only
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Lowton, Karen, 2005. "Trials and tribulations: Understanding motivations for clinical research participation amongst adults with cystic fibrosis," Social Science & Medicine, Elsevier, vol. 61(8), pages 1854-1865, October.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Ana Judith Blanco & Mark A. Micek & Lisa M. Frenkel & Pablo Montoya & Marina Karagianis & Laurinda Matunha & Wendy Johnson & Stephen Gloyd & James Pfeiffer, 2015. "Loss to Follow-Up Among HIV-Exposed Children in an HIV Clinic in Beira, Mozambique," SAGE Open, , vol. 5(3), pages 21582440155, July.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Lawton, Julia & Jenkins, Nicholas & Darbyshire, Julie & Farmer, Andrew & Holman, Rury & Hallowell, Nina, 2012. "Understanding the outcomes of multi-centre clinical trials: A qualitative study of health professional experiences and views," Social Science & Medicine, Elsevier, vol. 74(4), pages 574-581.
    2. Christofides, Emily & Dobson, Jennifer A. & Solomon, Melinda & Waters, Valerie & O’Doherty, Kieran C., 2016. "Heuristic decision-making about research participation in children with cystic fibrosis," Social Science & Medicine, Elsevier, vol. 162(C), pages 32-40.
    3. Fisher, Jill A. & Cottingham, Marci D. & Kalbaugh, Corey A., 2015. "Peering into the pharmaceutical “pipeline”: Investigational drugs, clinical trials, and industry priorities," Social Science & Medicine, Elsevier, vol. 131(C), pages 322-330.
    4. Dixon-Woods, Mary & Tarrant, Carolyn, 2009. "Why do people cooperate with medical research? Findings from three studies," Social Science & Medicine, Elsevier, vol. 68(12), pages 2215-2222, June.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:socmed:v:68:y:2009:i:6:p:1069-1074. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Catherine Liu (email available below). General contact details of provider: http://www.elsevier.com/wps/find/journaldescription.cws_home/315/description#description .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.