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Causes and demographic, medical, lifestyle and psychosocial predictors of premature mortality: the CARDIA study

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  • Iribarren, Carlos
  • Jacobs, David R.
  • Kiefe, Catarina I.
  • Lewis, Cora E.
  • Matthews, Karen A.
  • Roseman, Jeffrey M.
  • Hulley, Stephen B.

Abstract

We examined the 16-year mortality experience among participants in the baseline examination (1985-86) of the Coronary Artery Risk Development in Young Adults (CARDIA) Study, a U.S. cohort of 5115 urban adults initially 18-30 years old and balanced by sex and race (black and whites) in the USA. We observed 127 deaths (annual mortality of 0.15%). Compared to white women, the rate ratio (95% confidence interval) of all-cause mortality was 9.3 (4.4, 19.4) among black men, 5.3 (2.5, 11.4) among white men and 2.7 (1.2, 6.1) among black women. The predominant causes of death, which also differed greatly by sex-race, were AIDS (28% of deaths), homicide (16%), unintentional injury (10%), suicide (7%), cancer (7%) and coronary disease (7%). The significant baseline predictors of all-cause mortality in multivariate analysis were male sex, black race, diabetes, self-reported liver and kidney disease, current cigarette smoking and low social support. Two other factors, self-reported thyroid disease and high hostility, were significant predictors in analyses adjusted for age, sex and race. In conclusion, we found striking differences in the rates and underlying cause of death across sex-race groups and several independent predictors of young adult mortality that have major implications for preventive medicine and social policies.

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  • Iribarren, Carlos & Jacobs, David R. & Kiefe, Catarina I. & Lewis, Cora E. & Matthews, Karen A. & Roseman, Jeffrey M. & Hulley, Stephen B., 2005. "Causes and demographic, medical, lifestyle and psychosocial predictors of premature mortality: the CARDIA study," Social Science & Medicine, Elsevier, vol. 60(3), pages 471-482, February.
    • Handle: RePEc:eee:socmed:v:60:y:2005:i:3:p:471-482
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    1. Shor, Eran & Roelfs, David J., 2015. "Social contact frequency and all-cause mortality: A meta-analysis and meta-regression," Social Science & Medicine, Elsevier, vol. 128(C), pages 76-86.
    2. Fredrica Nyqvist & Bernd Pape & Tony Pellfolk & Anna Forsman & Kristian Wahlbeck, 2014. "Structural and Cognitive Aspects of Social Capital and All-Cause Mortality: A Meta-Analysis of Cohort Studies," Social Indicators Research: An International and Interdisciplinary Journal for Quality-of-Life Measurement, Springer, vol. 116(2), pages 545-566, April.
    3. Eran Shor & David Roelfs & Misty Curreli & Lynn Clemow & Matthew Burg & Joseph Schwartz, 2012. "Widowhood and Mortality: A Meta-Analysis and Meta-Regression," Demography, Springer;Population Association of America (PAA), vol. 49(2), pages 575-606, May.
    4. Shor, Eran & Roelfs, David J. & Bugyi, Paul & Schwartz, Joseph E., 2012. "Meta-analysis of marital dissolution and mortality: Reevaluating the intersection of gender and age," Social Science & Medicine, Elsevier, vol. 75(1), pages 46-59.
    5. Kroenke, Candyce, 2008. "Socioeconomic status and health: Youth development and neomaterialist and psychosocial mechanisms," Social Science & Medicine, Elsevier, vol. 66(1), pages 31-42, January.

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