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The associations of socioeconomic position with structural brain damage and connectivity and cognitive functioning: The Maastricht Study

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  • Geraets, Anouk F.J.
  • Schram, Miranda T.
  • Jansen, Jacobus F.A.
  • Köhler, Sebastian
  • van Boxtel, Martin P.J.
  • Eussen, Simone J.P.M.
  • Koster, Annemarie
  • Stehouwer, Coen D.A.
  • Bosma, Hans
  • Leist, Anja K.

Abstract

Socioeconomic inequalities in cognitive impairment may partly act through structural brain damage and reduced connectivity. This study investigated the extent to which the association of early-life socioeconomic position (SEP) with later-life cognitive functioning is mediated by later-life SEP, and whether the associations of SEP with later-life cognitive functioning can be explained by structural brain damage and connectivity.

Suggested Citation

  • Geraets, Anouk F.J. & Schram, Miranda T. & Jansen, Jacobus F.A. & Köhler, Sebastian & van Boxtel, Martin P.J. & Eussen, Simone J.P.M. & Koster, Annemarie & Stehouwer, Coen D.A. & Bosma, Hans & Leist, , 2024. "The associations of socioeconomic position with structural brain damage and connectivity and cognitive functioning: The Maastricht Study," Social Science & Medicine, Elsevier, vol. 355(C).
    • Handle: RePEc:eee:socmed:v:355:y:2024:i:c:s0277953624005641
    DOI: 10.1016/j.socscimed.2024.117111
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    References listed on IDEAS

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    1. Alison D Murray & Christopher J McNeil & Sima Salarirad & Lawrence J Whalley & Roger T Staff, 2014. "Early Life Socioeconomic Circumstance and Late Life Brain Hyperintensities – A Population Based Cohort Study," PLOS ONE, Public Library of Science, vol. 9(2), pages 1-7, February.
    2. Ryan J Dougherty & Justine Moonen & Kristine Yaffe & Stephen Sidney & Christos Davatzikos & Mohamad Habes & Lenore J Launer, 2020. "Smoking mediates the relationship between SES and brain volume: The CARDIA study," PLOS ONE, Public Library of Science, vol. 15(9), pages 1-11, September.
    3. Katherine J Ford & Lindsay C Kobayashi & Anja K Leist, 2022. "Childhood Socioeconomic Disadvantage and Pathways to Memory Performance in Mid to Late Adulthood: What Matters Most?," The Journals of Gerontology: Series B, The Gerontological Society of America, vol. 77(8), pages 1478-1489.
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