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Customizing immunization clinic operations to minimize open vial waste

Author

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  • Mofrad, Maryam H.
  • Garcia, Gian-Gabriel P.
  • Maillart, Lisa M.
  • Norman, Bryan A.
  • Rajgopal, Jayant

Abstract

Many multi-dose vaccine vials must be used within hours of reconstitution; unused doses are discarded as “open vial waste.” Building on Mofrad et al. (2014), we evaluate operating strategies that maximize coverage by controlling open vial waste. We define novel metrics for determining thresholds on vaccination clinic operating hours and session frequency. We study the performance of optimal and heuristic policies in the presence of random vial yield. Cost analyses indicate significant potential savings. Because optimal strategies are context specific, we also develop a decision support tool (available online) to easily replicate the analysis for any problem setting.

Suggested Citation

  • Mofrad, Maryam H. & Garcia, Gian-Gabriel P. & Maillart, Lisa M. & Norman, Bryan A. & Rajgopal, Jayant, 2016. "Customizing immunization clinic operations to minimize open vial waste," Socio-Economic Planning Sciences, Elsevier, vol. 54(C), pages 1-17.
    • Handle: RePEc:eee:soceps:v:54:y:2016:i:c:p:1-17
    DOI: 10.1016/j.seps.2015.10.007
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    References listed on IDEAS

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    1. Maryam Mofrad & Lisa Maillart & Bryan Norman & Jayant Rajgopal, 2014. "Dynamically optimizing the administration of vaccines from multi-dose vials," IISE Transactions, Taylor & Francis Journals, vol. 46(7), pages 623-635.
    2. Aswin Dhamodharan & Ruben Proano, 2012. "Determining the optimal vaccine vial size in developing countries: a Monte Carlo simulation approach," Health Care Management Science, Springer, vol. 15(3), pages 188-196, September.
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    Cited by:

    1. De Boeck, Kim & Decouttere, Catherine & Vandaele, Nico, 2020. "Vaccine distribution chains in low- and middle-income countries: A literature review," Omega, Elsevier, vol. 97(C).
    2. Zahra Azadi & Harsha Gangammanavar & Sandra Eksioglu, 2020. "Developing childhood vaccine administration and inventory replenishment policies that minimize open vial wastage," Annals of Operations Research, Springer, vol. 292(1), pages 215-247, September.

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