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Stability of limit cycles in a pluripotent stem cell dynamics model

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  • Adimy, Mostafa
  • Crauste, Fabien
  • Halanay, Andrei
  • Neamţu, Mihaela
  • Opriş, Dumitru

Abstract

This paper is devoted to the study of the stability of limit cycles of a nonlinear delay differential equation with a distributed delay. The equation arises from a model of population dynamics describing the evolution of a pluripotent stem cells population. We study the local asymptotic stability of the unique nontrivial equilibrium of the delay equation and we show that its stability can be lost through a Hopf bifurcation. We then investigate the stability of the limit cycles yielded by the bifurcation using the normal form theory and the center manifold theorem. We illustrate our results with some numerics.

Suggested Citation

  • Adimy, Mostafa & Crauste, Fabien & Halanay, Andrei & Neamţu, Mihaela & Opriş, Dumitru, 2006. "Stability of limit cycles in a pluripotent stem cell dynamics model," Chaos, Solitons & Fractals, Elsevier, vol. 27(4), pages 1091-1107.
  • Handle: RePEc:eee:chsofr:v:27:y:2006:i:4:p:1091-1107
    DOI: 10.1016/j.chaos.2005.04.083
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    Cited by:

    1. Merdan, H. & Duman, O., 2009. "On the stability analysis of a general discrete-time population model involving predation and Allee effects," Chaos, Solitons & Fractals, Elsevier, vol. 40(3), pages 1169-1175.
    2. Singh, Vimal, 2007. "A new frequency-domain criterion for elimination of limit cycles in fixed-point state-space digital filters using saturation arithmetic," Chaos, Solitons & Fractals, Elsevier, vol. 34(3), pages 813-816.
    3. Duman, O. & Merdan, H., 2009. "Stability analysis of continuous population model involving predation and Allee effect," Chaos, Solitons & Fractals, Elsevier, vol. 41(3), pages 1218-1222.
    4. Eva Kaslik & Mihaela Neamţu & Loredana Flavia Vesa, 2021. "Global Stability Analysis of a Five-Dimensional Unemployment Model with Distributed Delay," Mathematics, MDPI, vol. 9(23), pages 1-15, November.
    5. Çelik, C. & Merdan, H. & Duman, O. & Akın, Ö., 2008. "Allee effects on population dynamics with delay," Chaos, Solitons & Fractals, Elsevier, vol. 37(1), pages 65-74.
    6. Singh, Vimal, 2008. "Suppression of limit cycles in second-order companion form digital filters with saturation arithmetic," Chaos, Solitons & Fractals, Elsevier, vol. 36(3), pages 677-681.
    7. Mihalaş, Gh.I. & Neamţu, M. & Opriş, D. & Horhat, R.F., 2006. "A dynamic P53-MDM2 model with time delay," Chaos, Solitons & Fractals, Elsevier, vol. 30(4), pages 936-945.
    8. Culda, Loredana Camelia & Kaslik, Eva & Neamţu, Mihaela, 2022. "Stability and bifurcations in a general Cournot duopoly model with distributed time delays," Chaos, Solitons & Fractals, Elsevier, vol. 162(C).
    9. Kaslik, Eva & Neamţu, Mihaela & Vesa, Loredana Flavia, 2021. "Global stability analysis of an unemployment model with distributed delay," Mathematics and Computers in Simulation (MATCOM), Elsevier, vol. 185(C), pages 535-546.
    10. Bottani, Samuel & Grammaticos, Basile, 2008. "A simple model of genetic oscillations through regulated degradation," Chaos, Solitons & Fractals, Elsevier, vol. 38(5), pages 1468-1482.
    11. Kaslik, Eva & Neamţu, Mihaela, 2020. "Dynamics of a tourism sustainability model with distributed delay," Chaos, Solitons & Fractals, Elsevier, vol. 133(C).
    12. Singh, Vimal, 2008. "Novel frequency-domain criterion for elimination of limit cycles in a class of digital filters with single saturation nonlinearity," Chaos, Solitons & Fractals, Elsevier, vol. 38(1), pages 178-183.
    13. Singh, Vimal, 2007. "Modified LMI condition for the realization of limit cycle-free digital filters using saturation arithmetic," Chaos, Solitons & Fractals, Elsevier, vol. 32(4), pages 1448-1453.

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