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A Doubly Robust Censoring Unbiased Transformation

Author

Listed:
  • Rubin Daniel

    (University of California, Berkeley)

  • van der Laan Mark J.

    (Division of Biostatistics, School of Public Health, University of California, Berkeley)

Abstract

We consider random design nonparametric regression when the response variable is subject to right censoring. Following the work of Fan and Gijbels (1994), a common approach to this problem is to apply what has been termed a censoring unbiased transformation to the data to obtain surrogate responses, and then enter these surrogate responses with covariate data into standard smoothing algorithms. Existing censoring unbiased transformations generally depend on either the conditional survival function of the response of interest, or that of the censoring variable. We show that a mapping introduced in another statistical context is in fact a censoring unbiased transformation with a beneficial double robustness property, in that it can be used for nonparametric regression if either of these two conditional distributions are estimated accurately. Advantages of using this transformation for smoothing are illustrated in simulations and on the Stanford heart transplant data.

Suggested Citation

  • Rubin Daniel & van der Laan Mark J., 2007. "A Doubly Robust Censoring Unbiased Transformation," The International Journal of Biostatistics, De Gruyter, vol. 3(1), pages 1-21, March.
  • Handle: RePEc:bpj:ijbist:v:3:y:2007:i:1:n:4
    DOI: 10.2202/1557-4679.1052
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    Cited by:

    1. Abhinandan Dalal & Patrick Blobaum & Shiva Kasiviswanathan & Aaditya Ramdas, 2024. "Anytime-Valid Inference for Double/Debiased Machine Learning of Causal Parameters," Papers 2408.09598, arXiv.org, revised Sep 2024.
    2. I Díaz & O Savenkov & K Ballman, 2018. "Targeted learning ensembles for optimal individualized treatment rules with time-to-event outcomes," Biometrika, Biometrika Trust, vol. 105(3), pages 723-738.
    3. Kara E. Rudolph & Iván Díaz, 2022. "When the ends do not justify the means: Learning who is predicted to have harmful indirect effects," Journal of the Royal Statistical Society Series A, Royal Statistical Society, vol. 185(S2), pages 573-589, December.
    4. Michael Zimmert & Michael Lechner, 2019. "Nonparametric estimation of causal heterogeneity under high-dimensional confounding," Papers 1908.08779, arXiv.org.
    5. Jann Spiess & Vasilis Syrgkanis & Victor Yaneng Wang, 2021. "Finding Subgroups with Significant Treatment Effects," Papers 2103.07066, arXiv.org, revised Dec 2023.

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