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Bayesian Optimal Designs for Phase I Clinical Trials

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  • Linda M. Haines
  • Inna Perevozskaya
  • William F. Rosenberger

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  • Linda M. Haines & Inna Perevozskaya & William F. Rosenberger, 2003. "Bayesian Optimal Designs for Phase I Clinical Trials," Biometrics, The International Biometric Society, vol. 59(3), pages 591-600, September.
    • Handle: RePEc:bla:biomet:v:59:y:2003:i:3:p:591-600
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    File URL: http://hdl.handle.net/10.1111/1541-0420.00069
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    References listed on IDEAS

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    1. Silvio S. Zocchi & Anthony C. Atkinson, 1999. "Optimum Experimental Designs for Multinomial Logistic Models," Biometrics, The International Biometric Society, vol. 55(2), pages 437-444, June.
    2. Robert K. Tsutakawa, 1980. "Selection of Dose Levels for Estimating a Percentage Point of a Logistic Quantal Response Curve," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 29(1), pages 25-33, March.
    3. Mauro Gasparini & Jeffrey Eisele, 2000. "A Curve-Free Method for Phase I Clinical Trials," Biometrics, The International Biometric Society, vol. 56(2), pages 609-615, June.
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    Cited by:

    1. Alessandra Giovagnoli, 2021. "The Bayesian Design of Adaptive Clinical Trials," IJERPH, MDPI, vol. 18(2), pages 1-15, January.
    2. Dette, Holger & Biedermann, Stefanie & Zhu, Wei, 2005. "Geometric construction of optimal designs for dose-responsemodels with two parameters," Technical Reports 2005,08, Technische Universität Dortmund, Sonderforschungsbereich 475: Komplexitätsreduktion in multivariaten Datenstrukturen.
    3. Daniel R. Cavagnaro & Richard Gonzalez & Jay I. Myung & Mark A. Pitt, 2013. "Optimal Decision Stimuli for Risky Choice Experiments: An Adaptive Approach," Management Science, INFORMS, vol. 59(2), pages 358-375, February.
    4. Oron Assaf P. & Azriel David & Hoff Peter D., 2011. "Dose-Finding Designs: The Role of Convergence Properties," The International Journal of Biostatistics, De Gruyter, vol. 7(1), pages 1-17, October.
    5. Guosheng Yin & Ying Yuan, 2009. "A Latent Contingency Table Approach to Dose Finding for Combinations of Two Agents," Biometrics, The International Biometric Society, vol. 65(3), pages 866-875, September.
    6. Jay Bartroff & Tze Leung Lai, 2011. "Incorporating Individual and Collective Ethics into Phase I Cancer Trial Designs," Biometrics, The International Biometric Society, vol. 67(2), pages 596-603, June.
    7. Azriel, David, 2014. "Optimal sequential designs in phase I studies," Computational Statistics & Data Analysis, Elsevier, vol. 71(C), pages 288-297.
    8. Dette, Holger & Biedermann, Stefanie & Zhu, Wei, 2004. "Optimal designs for dose-response models with restricted design spaces," Technical Reports 2004,40, Technische Universität Dortmund, Sonderforschungsbereich 475: Komplexitätsreduktion in multivariaten Datenstrukturen.
    9. Dette, Holger & Biedermann, Stefanie & Zhu, Wei, 2005. "Compound Optimal Designs for Percentile Estimation in Dose-Response Models with Restricted Design Intervals," Technical Reports 2005,02, Technische Universität Dortmund, Sonderforschungsbereich 475: Komplexitätsreduktion in multivariaten Datenstrukturen.

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