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Design and Analysis of Group-Randomized Trials: A Review of Recent Practices

Author

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  • Varnell, S.P.
  • Murray, D.M.
  • Janega, J.B.
  • Blitstein, J.L.

Abstract

We reviewed group-randomized trials (GRTs) published in the American Journal of Public Health and Preventive Medicine from 1998 through 2002 and estimated the proportion of GRTs that employ appropriate methods for design and analysis. Of 60 articles, 9 (15.0%) reported evidence of using appropriate methods for sample size estimation. Of 59 articles in the analytic review, 27 (45.8%) reported at least 1 inappropriate analysis and 12 (20.3%) reported only inappropriate analyses. Nineteen (32.2%) reported analyses at an individual or subgroup level, ignoring group, or included group as a fixed effect. Hence increased vigilance is needed to ensure that appropriate methods for GRTs are employed and that results based on inappropriate methods are not published.

Suggested Citation

  • Varnell, S.P. & Murray, D.M. & Janega, J.B. & Blitstein, J.L., 2004. "Design and Analysis of Group-Randomized Trials: A Review of Recent Practices," American Journal of Public Health, American Public Health Association, vol. 94(3), pages 393-399.
    • Handle: RePEc:aph:ajpbhl:2004:94:3:393-399_0
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    Cited by:

    1. Jonathan L. Blitstein & Peter J. Hannan & David M. Murray & William R. Shadish, 2005. "Increasing the Degrees of Freedom in Existing Group Randomized Trials," Evaluation Review, , vol. 29(3), pages 241-267, June.
    2. Jonathan L. Blitstein & David M. Murray & Peter J. Hannan & William R. Shadish, 2005. "Increasing the Degrees of Freedom in Future Group Randomized Trials," Evaluation Review, , vol. 29(3), pages 268-286, June.
    3. Ruoxuan Xiong & Susan Athey & Mohsen Bayati & Guido Imbens, 2024. "Optimal Experimental Design for Staggered Rollouts," Management Science, INFORMS, vol. 70(8), pages 5317-5336, August.
    4. Steven Teerenstra & Bing Lu & John S. Preisser & Theo van Achterberg & George F. Borm, 2010. "Sample Size Considerations for GEE Analyses of Three-Level Cluster Randomized Trials," Biometrics, The International Biometric Society, vol. 66(4), pages 1230-1237, December.
    5. repec:mpr:mprres:4632 is not listed on IDEAS
    6. Winfried Zinn & Sebastian Sauer & Richard Göllner, 2016. "The German Inpatient Satisfaction Scale," SAGE Open, , vol. 6(2), pages 21582440166, April.
    7. Randall Juras, 2016. "Estimates of Intraclass Correlation Coefficients and Other Design Parameters for Studies of School-Based Nutritional Interventions," Evaluation Review, , vol. 40(4), pages 314-333, August.
    8. Ji-Hyun Lee & Michael J Schell & Richard Roetzheim, 2009. "Analysis of Group Randomized Trials with Multiple Binary Endpoints and Small Number of Groups," PLOS ONE, Public Library of Science, vol. 4(10), pages 1-9, October.
    9. Peter Z. Schochet, "undated". "Statistical Power for Random Assignment Evaluations of Education Programs," Mathematica Policy Research Reports 6749d31ad72d4acf988f7dce5, Mathematica Policy Research.
    10. Benjamin F. Arnold & Francois Rerolle & Christine Tedijanto & Sammy M. Njenga & Mahbubur Rahman & Ayse Ercumen & Andrew Mertens & Amy J. Pickering & Audrie Lin & Charles D. Arnold & Kishor Das & Chris, 2024. "Geographic pair matching in large-scale cluster randomized trials," Nature Communications, Nature, vol. 15(1), pages 1-15, December.
    11. van der Laan Mark J. & Petersen Maya & Zheng Wenjing, 2013. "Estimating the Effect of a Community-Based Intervention with Two Communities," Journal of Causal Inference, De Gruyter, vol. 1(1), pages 83-106, June.
    12. Paul Branscum & Manoj Sharma, 2012. "After-School Based Obesity Prevention Interventions: A Comprehensive Review of the Literature," IJERPH, MDPI, vol. 9(4), pages 1-20, April.

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