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Treatment for glaucoma: Adherence by the elderly

Author

Listed:
  • Gurwitz, J.H.
  • Glynn, R.J.
  • Monane, M.
  • Everitt, D.E.
  • Gilden, D.
  • Smith, N.
  • Avorn, J.

Abstract

Objectives. The purpose of this study was to determine the extent of nonadherence to treatment for glaucoma among elderly patients. Methods. This was a retrospective cohort study of 2440 patients older than age 65 who were enrolled in the New Jersey Medicaid Program and who were newly initiated on a topical agent for the treatment of glaucoma. Two patient-specific measures of nonadherence were employed: (1) no filled prescription for any glaucoma medication over a 12-month period after the initiation of therapy and (2) number of days without therapy for glaucoma during this 12-month period. Results. By the first measure, 569 patients (23%) were found to be nonadherent. The mean number of days without therapy during the study year was 112. Factors associated with nonadherence included the use of glaucoma medication requiring more than 2 administrations per day and the presence of multiple other medications in the patient's drug regimen. Patients started on multiple glaucoma medications were more adherent than those started on a single agent. Age and sex were not found to be predictors of nonadherence. Conclusions. Substantial nonadherence was found to be common in this population. More attention to the issue of nonadherence could result in important benefits in the preservation of sight.

Suggested Citation

  • Gurwitz, J.H. & Glynn, R.J. & Monane, M. & Everitt, D.E. & Gilden, D. & Smith, N. & Avorn, J., 1993. "Treatment for glaucoma: Adherence by the elderly," American Journal of Public Health, American Public Health Association, vol. 83(5), pages 711-716.
    • Handle: RePEc:aph:ajpbhl:1993:83:5:711-716_5
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    Cited by:

    1. Stefanie Frech & Daniel Kreft & Rudolf F Guthoff & Gabriele Doblhammer, 2018. "Pharmacoepidemiological assessment of adherence and influencing co-factors among primary open-angle glaucoma patients—An observational cohort study," PLOS ONE, Public Library of Science, vol. 13(1), pages 1-14, January.
    2. Michael Iskedjian & David Covert & John Walker, 2011. "Persistence with Prostaglandin Agonist Use with and without Adjunctive Therapy for Glaucoma Patients," The Patient: Patient-Centered Outcomes Research, Springer;International Academy of Health Preference Research, vol. 4(2), pages 133-141, June.
    3. Yunjeong Jang & Donghyun Jee & Donghwan Lee & Nam-Kyong Choi & SeungJin Bae, 2021. "Medication Adherence and Persistence of Open-Angle Glaucoma Patients in Korea: A Retrospective Study Using National Health Insurance Claims Data," IJERPH, MDPI, vol. 18(8), pages 1-12, April.

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