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How genes and the social environment moderate each other

Author

Listed:
  • Reiss, D.
  • Leve, L.D.
  • Neiderhiser, J.M.

Abstract

Recent research has suggested that the social environment can moderate the expression of genetic influences on health and that genetic influences can shape an individual's sensitivity to the social environment. Evidence supports 4 major mechanisms: genes can influence an individual's response to environmental stress, genes may enhance an individual's sensitivity to both favorable and adverse environments, inherited characteristics may better fit with some environments than with others, and inherited capabilitiesmay only become manifest in challenging or responsive environments. Further progress depends on better recognition of patterns of gene-environment interaction, improved methods of assessing the environment and its impact on geneticmechanisms, the use of appropriately designed laboratory studies, identification of heritable differences in an individual before environmental moderation occurs, and clarification of the timing of the impact of social and genetic moderation.

Suggested Citation

  • Reiss, D. & Leve, L.D. & Neiderhiser, J.M., 2013. "How genes and the social environment moderate each other," American Journal of Public Health, American Public Health Association, vol. 103(SUPPL.1), pages 111-121.
    • Handle: RePEc:aph:ajpbhl:10.2105/ajph.2013.301408_5
    DOI: 10.2105/AJPH.2013.301408
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    Cited by:

    1. Bierut, Laura & Biroli, Pietro & Galama, Titus J. & Thom, Kevin, 2023. "Challenges in studying the interplay of genes and environment. A study of childhood financial distress moderating genetic predisposition for peak smoking," Journal of Economic Psychology, Elsevier, vol. 98(C).
    2. Liu, S.Y. & Walter, S. & Marden, J. & Rehkopf, D.H. & Kubzansky, L.D. & Nguyen, T. & Glymour, M.M., 2015. "Genetic vulnerability to diabetes and obesity: Does education offset the risk?," Social Science & Medicine, Elsevier, vol. 127(C), pages 150-158.
    3. Marion Spengler & Juliana Gottschling & Elisabeth Hahn & Elliot M Tucker-Drob & Claudia Harzer & Frank M Spinath, 2018. "Does the heritability of cognitive abilities vary as a function of parental education? Evidence from a German twin sample," PLOS ONE, Public Library of Science, vol. 13(5), pages 1-15, May.
    4. Kim, Jinho & Kim, Rockli & Oh, Hannah & Lippert, Adam M. & Subramanian, S.V., 2020. "Estimating the influence of adolescent delinquent behavior on adult health using sibling fixed effects," Social Science & Medicine, Elsevier, vol. 265(C).

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