IDEAS home Printed from https://ideas.repec.org/a/aph/ajpbhl/10.2105-ajph.2009.162982_5.html
   My bibliography  Save this article

Disparate inclusion of older adults in clinical trials: priorities and opportunities for policy and practice change

Author

Listed:
  • Herrera, A.P.
  • Snipes, S.A.
  • King, D.W.
  • Torres-Vigil, I.
  • Goldberg, D.S.
  • Wenberg, A.D.

Abstract

Older adults are vastly underrepresented in clinical trials in spite of shouldering a disproportionate burden of disease and consumption of prescription drugs and therapies, restricting treatments' generalizability, efficacy, and safety. Eliminating Disparities in Clinical Trials, a national initiative comprising a stakeholder network of researchers, community advocates, policymakers, and federal representatives, undertook, a critical analysis of older adults' structural barriers to clinical trial participation. We present practice and policy change recommendations emerging from this process and their rationale, which spanned multiple themes: (1) decision making with cognitively impaired patients; (2) pharmacokinetic differences and physiological age; (3) health literacy, communication, and aging; (4) geriatric training; (5) federal monitoring and accountability; (6) clinical trial costs; and (7) cumulative effects of aging and ethnicity. Chronic Disease Revention and Control Research.

Suggested Citation

  • Herrera, A.P. & Snipes, S.A. & King, D.W. & Torres-Vigil, I. & Goldberg, D.S. & Wenberg, A.D., 2010. "Disparate inclusion of older adults in clinical trials: priorities and opportunities for policy and practice change," American Journal of Public Health, American Public Health Association, vol. 100(S1), pages 105-112.
    • Handle: RePEc:aph:ajpbhl:10.2105/ajph.2009.162982_5
    DOI: 10.2105/AJPH.2009.162982
    as

    Download full text from publisher

    File URL: http://hdl.handle.net/10.2105/AJPH.2009.162982
    Download Restriction: no
    File URL: https://libkey.io/10.2105/AJPH.2009.162982?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Liat Ayalon, 2020. "Life in a world for all ages: From a utopic idea to reality," Journal of Elder Policy, John Wiley & Sons, vol. 1(1), pages 39-67, June.
    2. Valentyn Litvin, 2020. "When ignorance is bliss: Intentional agnosticism in drug approval," Health Economics, John Wiley & Sons, Ltd., vol. 29(2), pages 185-194, February.
    3. Lorraine Greaves & Andreea C. Brabete & Mira Maximos & Ella Huber & Alice Li & Mê-Linh Lê & Sherif Eltonsy & Madeline Boscoe, 2023. "Sex, Gender, and the Regulation of Prescription Drugs: Omissions and Opportunities," IJERPH, MDPI, vol. 20(4), pages 1-19, February.
    4. Jesse M. Bell & Tina M. Mason & Harleah G. Buck & Cindy S. Tofthagen & Allyson R. Duffy & Maureen W. Groër & James P. McHale & Kevin E. Kip, 2021. "Challenges in Obtaining and Assessing Salivary Cortisol and α-Amylase in an Over 60 Population Undergoing Psychotherapeutic Treatment for Complicated Grief: Lessons Learned," Clinical Nursing Research, , vol. 30(5), pages 680-689, June.
    5. Valérie Seegers & Ludovic Trinquart & Isabelle Boutron & Philippe Ravaud, 2013. "Comparison of Treatment Effect Estimates for Pharmacological Randomized Controlled Trials Enrolling Older Adults Only and Those including Adults: A Meta-Epidemiological Study," PLOS ONE, Public Library of Science, vol. 8(5), pages 1-5, May.
    6. Divyanshu Raheja & Evelyn P. Davila & Eric T. Johnson & Rijalda Deović & Michele Paine & Nadine Rouphael, 2018. "Willingness to Participate in Vaccine-Related Clinical Trials among Older Adults," IJERPH, MDPI, vol. 15(8), pages 1-12, August.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:aph:ajpbhl:10.2105/ajph.2009.162982_5. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Christopher F Baum (email available below). General contact details of provider: https://www.apha.org .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.