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Telomeres are structures at the ends of eukaryotic chromosomes and consist of tandemly repeated DNA sequences. Telomeres shorten with each cell division, and it is well known that telomere length in peripheral blood mononuclear cells (PBMCs) decreases with age. High oxidative stress can lead to accelerated telomere shortening, which causes premature cell senescence. In summary, this review shows the short Telomere Length has been identified in a limited number of population studies as a risk factor for development of T2DM

Author

Listed:
  • Murillo Ortiz Blanca

    (High Specialty Medical Unit, Instituto Mexicano Social security, Mexico)

  • Martínez Garza Sandra

    (High Specialty Medical Unit, Instituto Mexicano Social security, Mexico)

Abstract

The present review focused on the most important metabolic disorder which is affecting every fourth of the diabetic, and is known as diabetic nephropathy. This review focused on the hypertension in diabetic nephropathy, its clinical aspects, management and guidelines. Hypertension is the most common phenomenon in diabetics.

Suggested Citation

  • Murillo Ortiz Blanca & Martínez Garza Sandra, 2017. "Telomeres are structures at the ends of eukaryotic chromosomes and consist of tandemly repeated DNA sequences. Telomeres shorten with each cell division, and it is well known that telomere length in p," Current Research in Diabetes & Obesity Journal, Juniper Publishers Inc., vol. 2(1), pages 15-17, April.
    • Handle: RePEc:adp:jcrdoj:v:2:y:2017:i:1:p:15-17
    DOI: 10.19080/CRDOJ.2017.02.555580
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    References listed on IDEAS

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    1. Peter Willeit & Julia Raschenberger & Emma E Heydon & Sotirios Tsimikas & Margot Haun & Agnes Mayr & Siegfried Weger & Joseph L Witztum & Adam S Butterworth & Johann Willeit & Florian Kronenberg & Ste, 2014. "Leucocyte Telomere Length and Risk of Type 2 Diabetes Mellitus: New Prospective Cohort Study and Literature-Based Meta-Analysis," PLOS ONE, Public Library of Science, vol. 9(11), pages 1-9, November.
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    More about this item

    Keywords

    juniper publishers; diabetes journals; diabetes impact factor; endocrinology journal; endocrinology impact factor; endocrinology research journal; endocrinology research articles; diabetes open access journals; Obesity Journal; Diabetes & Obesity Journal;
    All these keywords.

    JEL classification:

    • R00 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General - - - General
    • Z0 - Other Special Topics - - General

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