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GATA Transcription Factors in Hematological System

Author

Listed:
  • Wilairat Leeanansaksiri

    (School of Preclinic, Institute of Science, Suranaree University of Technology, Thailand)

  • Chavaboon Dechsukhum

    (School of Pathology, Institute of Medicine, Suranaree University of Technology, Thailand)

Abstract

The zinc finger DNA binding GATA transcription factors are evolutionarily conserved among animals, plants and some microorganism. In human, there are 6 GATA members have been described: GATA-1/2/3/4/5/6. Among these GATAs, GATA1/2/3 are expressed in both hematopoietic lineage and non-hematopoietic cells while GATA 4/5/6 are expressed in non-hematotopoietic cells, particularly in the development of heart and gut. In this review, we mainly emphasis on only GATA1/2/3 in human blood system.

Suggested Citation

  • Wilairat Leeanansaksiri & Chavaboon Dechsukhum, 2024. "GATA Transcription Factors in Hematological System," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 56(3), pages 48068-48071, May.
    • Handle: RePEc:abf:journl:v:56:y:2024:i:3:p:48068-48071
    DOI: 10.26717/BJSTR.2024.56.008850
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