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Long-Term Cryopreservation of an Autologous Immunocomplex of Dendritic Cells and Cancer Antigen (HiDCV-OS1) that Stimulates Antitumor Immunity Against Chemotherapy-Resistant Ovarian Cancer

Author

Listed:
  • Masao Sasai

    (Frontier of Regenerative Medicine, Graduate School of Medicine, Osaka University, Japan
    Department of Medical Innovation, Osaka University Hospital, Japan)

  • Kyoso Ishida

    (Toyonaka Municipal Hospital, Japan)

  • Tomoyuki Nishikawa

    (Department of Device Application for Molecular Therapeutics, Graduate School of Medicine, Osaka University, Japan)

  • Chin Yang Chang

    (Department of Gene & Stem Cell Regenerative Therapy, Graduate School of Medicine, Osaka University, Japan)

  • Jiro Fujita

    (Department of Hematology and Oncology, Graduate School of Medicine, Osaka University, Japan)

  • Hiroki Higashihara

    (Center of Interventional Radiology, Osaka University Hospital, Japan)

  • Keigo Osuga

    (Department of Diagnostic Radiology, Osaka Medical and Pharmaceutical University, Japan)

  • Toshihiro Nakajima

    (Immunomedicine, Inc., Japan)

  • Kenjiro Sawada

    (Division of Obstetrics and Gynecology, Graduate School of Medicine, Osaka University, Japan)

  • Tadashi Kimura

    (Sakai City Medical Center, Japan)

  • Yasufumi Kaneda

    (Administration Bureau, Osaka University, Japan)

  • Kazuma Sakura

    (Respiratory Center, Osaka University Hospital, Japan)

Abstract

In recent years, therapies that use cellular products made from autologous tissues for medical treatment have been developed. Although novel treatments for ovarian cancer, such as a PARP inhibitor, have been developed and the prognosis has improved, for the relapse of ovarian cancer, efficient treatments are not developed for the relapse yet. We started a clinical trial of autologous cell processed products (HiDCVOS1), which were made from ovarian cancer cells and dendritic cells by using hemagglutinating virus of Japan envelope (HVJ-E).

Suggested Citation

  • Masao Sasai & Kyoso Ishida & Tomoyuki Nishikawa & Chin Yang Chang & Jiro Fujita & Hiroki Higashihara & Keigo Osuga & Toshihiro Nakajima & Kenjiro Sawada & Tadashi Kimura & Yasufumi Kaneda & Kazuma Sak, 2024. "Long-Term Cryopreservation of an Autologous Immunocomplex of Dendritic Cells and Cancer Antigen (HiDCV-OS1) that Stimulates Antitumor Immunity Against Chemotherapy-Resistant Ovarian Cancer," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 56(2), pages 47914-47917, April.
    • Handle: RePEc:abf:journl:v:56:y:2024:i:2:p:47914-47917
    DOI: 10.26717/BJSTR.2024.56.008830
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