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A Look Back at more than a Century of Progress in Oncology from the Tumor Cell to the Tumor Environment

Author

Listed:
  • Guy Lesec

    (Scientific Director, Spécialiste en Pathologie (FMH), Lausanne Cypa UNILABS, Biopôle 3, Route de la corniche 9A,1066 Epalinges (Suisse) VD, Switzerland)

  • Marie-Agnès Doucey

    (Directrice de recherche, Lausanne, Switzerland)

  • Carissa Chu

    (Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, USA)

  • Eugene Pietzak

    (Department of Urology, Weill Cornell Medical College, USA)

Abstract

During the first half of the 20th century, after the rediscovery of Mendel’s laws in 1900, there was a growing interest in determining how these laws of genetics applied, among other things, to mammalian inheritance. In 1909 Morgan’s decisive genetic work on the fruit fly, Drosophila melanogaster, with which his name would always be associated, began. Thus, from the beginning of the 20th century, even before the establishment of fundamental knowledge of cell and tissue biology, daring experimentalists sought to explore the nature of tumor tissue by performing intra- and interspecific tumor grafts. The generally very narrow specificity of a tumor for the organism on which it appeared was discussed as early as 1908 by Tyzzer in terms of Mendelian genetics [1].

Suggested Citation

  • Guy Lesec & Marie-Agnès Doucey & Carissa Chu & Eugene Pietzak, 2024. "A Look Back at more than a Century of Progress in Oncology from the Tumor Cell to the Tumor Environment," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 55(4), pages 47258-47269, March.
    • Handle: RePEc:abf:journl:v:55:y:2024:i:4:p:47258-47269
    DOI: 10.26717/BJSTR.2024.55.008741
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