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Negative Association between Diabetes Mellitus and the Efficacy of Cancer Immunotherapy

Author

Listed:
  • Raydonna Rachel Schneider

    (Department of Oncology, Jinan Central Hospital, Shandong University, China)

  • Ning Liu
  • Surui Liu
  • Meili Sun

    (Department of Oncology, Jinan Central Hospital, Shandong University, China
    Department of Oncology, Central Hospital Affiliated to Shandong First Medical University, China)

Abstract

Diabetes mellitus (DM) is one of the risk factors for poor prognosis and outcomes in cancer patients. This study aimed to explore the efficacy of tumor immunotherapy for cancer patients with comorbid diabetes. A systematic electronic search on keywords including immunotherapy and tumor patients with diabetes was performed through electronic databases including PubMed, Embase and Web of Science. The primary outcome was the overall survival (OS). The secondary outcomes were the progression-free survival (PFS). Four retrospective cohort studies were included for analysis: A total of 3065 cancer patients were enrolled, including 1509 patients with comorbid diabetes.

Suggested Citation

  • Raydonna Rachel Schneider & Ning Liu & Surui Liu & Meili Sun, 2024. "Negative Association between Diabetes Mellitus and the Efficacy of Cancer Immunotherapy," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 55(4), pages 47158-47165, March.
  • Handle: RePEc:abf:journl:v:55:y:2024:i:4:p:47158-47165
    DOI: 10.26717/BJSTR.2024.55.008726
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