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Histochemical Staining of Zn+2-Ions and Insulin in B-Cells of Isolated Pancreatic Islets, Cells of Prostate and Sallivan Glands

Author

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  • Meyramov G G
  • Meyramova A G

    (Diabetes Research Group, Karaganda, Kazakhstan)

Abstract

Pancreatic B-cells contain a large amount of Zn+2ions [1-3] as Salivary glands and prostate. In B-cells Zn+2-ions take part in processes of biosynthesis of insulin as at processes of storage by forming of Zn+2-insulin complex [4,5]. It is known that Zn+2-ions in B-cells formed with insulin, a deposited form of hormone as Zn+2-insulin complex [4]. Proinsulin forms a zinc contain hexamer soon after its synthesis. In addition, the Zn+2-ions enhance proinsulin’s solubility and render insulin insoluble.

Suggested Citation

  • Meyramov G G & Meyramova A G, 2024. "Histochemical Staining of Zn+2-Ions and Insulin in B-Cells of Isolated Pancreatic Islets, Cells of Prostate and Sallivan Glands," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 54(5), pages 46480-46485, February.
    • Handle: RePEc:abf:journl:v:54:y:2024:i:5:p:46480-46485
    DOI: 10.26717/BJSTR.2024.54.008625
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