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Medication Related Osteonecrosis of Jaw (MRONJ)- A Case Report of the Synergistic Effect of Pentoxifyllin and Tocopherol (PENTO Protocol) in Treatment of MRONJ

Author

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  • Aya Mostafa

    (Department of oral medicine and periodontology, College of dentistry, Ain shams University, Egypt)

Abstract

Osteonecrosis of jaw is a condition in which bone cells die due to various causes. It has several types one of them is Medication related osteonecrosis of the jaw (MRONJ). MRONJ significantly affects the patient’s quality of life and leads to a significant percentage of mortality. The treatment of osteonecrosis can be conservative, which aims to be beneficial for the patient’s quality of life, and surgical, which involves debridement of the necrotic bone. This article describes a case of a 60 years old female patient with necrotic segment of her mandibular jaw with no pain and a history of taking hormonal drug after stopping chemotherapy for 1 year. We have laid down a new non-surgical well tolerated treatment modality with minimal side effects.

Suggested Citation

  • Aya Mostafa, 2024. "Medication Related Osteonecrosis of Jaw (MRONJ)- A Case Report of the Synergistic Effect of Pentoxifyllin and Tocopherol (PENTO Protocol) in Treatment of MRONJ," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 54(4), pages 46101-46106, January.
    • Handle: RePEc:abf:journl:v:54:y:2024:i:4:p:46101-46106
    DOI: 10.26717/BJSTR.2024.54.008575
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