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Potential Application of Oligonucleotide Therapeutics in SARS-CoV-2 Genomic RNA Knockdown

Author

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  • Masahito Inagaki

    (Graduate School of Science, Nagoya University, Japan)

Abstract

Oligonucleotide therapeutics have received a lot of attention that can target diverse molecules. Antisense oligonucleotides are one of the oligonucleotide therapeutics that control genetic information transmission by binding to target messenger RNA (mRNA) and non-coding RNA (ncRNA) with complementary sequences. Antisense oligonucleotides act intracellularly and can target molecules that cannot be targeted with antibody drugs, so they are expected to be the next generation of molecular targeting drugs.

Suggested Citation

  • Masahito Inagaki, 2023. "Potential Application of Oligonucleotide Therapeutics in SARS-CoV-2 Genomic RNA Knockdown," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 53(5), pages 45126-45133, November.
  • Handle: RePEc:abf:journl:v:53:y:2023:i:5:p:45126-45133
    DOI: 10.26717/BJSTR.2023.53.008460
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