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Controlling the Headache Attacks in Special Subgroups of Migraine Patients. Preliminary Experience with SlowRelease L-Cysteine (Acetium® Capsules) that Eliminates Acetaldehyde, A Powerful Liberator of Histamine

Author

Listed:
  • Kari Syrjänen

    (SMW Consultants Ltd, Kaarina, Finland)

  • Markku Nissilä

    (Terveystalo Medical Centre, Turku, Finland)

  • Mikko Kallela

    (Medical Centre Aava, Helsinki, Finland)

  • Osmo Suovaniemi

    (Department of Clinical Research, Biohit Oyj, Helsinki, Finland)

Abstract

Testimonials received from migraine patients stated that L-cysteine (Acetium® Capsules) originally used for elimination of carcinogenic acetaldehyde in the stomach, prevented also their headache attacks. These endorsements prompted the company (Biohit Oyj, Helsinki) to formulate a hypothesis to explain these anti-migraine effects of Acetium® Capsules. It was reasoned that elimination of acetaldehyde (a potent liberator of histamine from tissue mast cells) by L-cysteine reduces the levels of histamine critically enough to arrest its availability to induce Nitric Oxide (NO), which is considered as the final trigger of migraine attacks.

Suggested Citation

  • Kari Syrjänen & Markku Nissilä & Mikko Kallela & Osmo Suovaniemi, 2023. "Controlling the Headache Attacks in Special Subgroups of Migraine Patients. Preliminary Experience with SlowRelease L-Cysteine (Acetium® Capsules) that Eliminates Acetaldehyde, A Powerful Liberator o," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 48(4), pages 40026-40032, February.
    • Handle: RePEc:abf:journl:v:48:y:2023:i:4:p:40026-40032
    DOI: 10.26717/BJSTR.2023.48.007700
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