Functional genomic landscape of acute myeloid leukaemia

Citations

Cited by:

1. Bofei Wang & Patrick K. Reville & Mhd Yousuf Yassouf & Fatima Z. Jelloul & Christopher Ly & Poonam N. Desai & Zhe Wang & Pamella Borges & Ivo Veletic & Enes Dasdemir & Jared K. Burks & Guilin Tang & S, 2024. "Comprehensive characterization of IFNγ signaling in acute myeloid leukemia reveals prognostic and therapeutic strategies," Nature Communications, Nature, vol. 15(1), pages 1-16, December.
2. W. Frank Lenoir & Micaela Morgado & Peter C. DeWeirdt & Megan McLaughlin & Audrey L. Griffith & Annabel K. Sangree & Marissa N. Feeley & Nazanin Esmaeili Anvar & Eiru Kim & Lori L. Bertolet & Medina C, 2021. "Discovery of putative tumor suppressors from CRISPR screens reveals rewired lipid metabolism in acute myeloid leukemia cells," Nature Communications, Nature, vol. 12(1), pages 1-15, December.
3. Tariq Kewan & Arda Durmaz & Waled Bahaj & Carmelo Gurnari & Laila Terkawi & Hussein Awada & Olisaemeka D. Ogbue & Ramsha Ahmed & Simona Pagliuca & Hassan Awada & Yasuo Kubota & Minako Mori & Ben Ponvi, 2023. "Molecular patterns identify distinct subclasses of myeloid neoplasia," Nature Communications, Nature, vol. 14(1), pages 1-10, December.
4. Rebekka Wegmann & Lorenz Bankel & Yasmin Festl & Kate Lau & Sohyon Lee & Fabian Arnold & Valentina Cappelletti & Aaron Fehr & Paola Picotti & Konstantin J. Dedes & Daniel Franzen & Daniela Lenggenhage, 2024. "Molecular and functional landscape of malignant serous effusions for precision oncology," Nature Communications, Nature, vol. 15(1), pages 1-21, December.
5. Elizabeth Heyes & Anna S. Wilhelmson & Anne Wenzel & Gabriele Manhart & Thomas Eder & Mikkel B. Schuster & Edwin Rzepa & Sachin Pundhir & Teresa D’Altri & Anne-Katrine Frank & Coline Gentil & Jakob Wo, 2023. "TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression," Nature Communications, Nature, vol. 14(1), pages 1-18, December.
6. Rebekka Wegmann & Ximena Bonilla & Ruben Casanova & Stéphane Chevrier & Ricardo Coelho & Cinzia Esposito & Joanna Ficek-Pascual & Sandra Goetze & Gabriele Gut & Francis Jacob & Andrea Jacobs & Jack Ku, 2024. "Single-cell landscape of innate and acquired drug resistance in acute myeloid leukemia," Nature Communications, Nature, vol. 15(1), pages 1-18, December.
7. J. McClatchy & R. Strogantsev & E. Wolfe & H. Y. Lin & M. Mohammadhosseini & B. A. Davis & C. Eden & D. Goldman & W. H. Fleming & P. Conley & G. Wu & L. Cimmino & H. Mohammed & A. Agarwal, 2023. "Clonal hematopoiesis related TET2 loss-of-function impedes IL1β-mediated epigenetic reprogramming in hematopoietic stem and progenitor cells," Nature Communications, Nature, vol. 14(1), pages 1-17, December.
8. Tea Pemovska & Johannes W. Bigenzahn & Ismet Srndic & Alexander Lercher & Andreas Bergthaler & Adrián César-Razquin & Felix Kartnig & Christoph Kornauth & Peter Valent & Philipp B. Staber & Giulio Sup, 2021. "Metabolic drug survey highlights cancer cell dependencies and vulnerabilities," Nature Communications, Nature, vol. 12(1), pages 1-19, December.
9. David Wang & Mathieu Quesnel-Vallieres & San Jewell & Moein Elzubeir & Kristen Lynch & Andrei Thomas-Tikhonenko & Yoseph Barash, 2023. "A Bayesian model for unsupervised detection of RNA splicing based subtypes in cancers," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
10. Brooks A. Benard & Logan B. Leak & Armon Azizi & Daniel Thomas & Andrew J. Gentles & Ravindra Majeti, 2021. "Clonal architecture predicts clinical outcomes and drug sensitivity in acute myeloid leukemia," Nature Communications, Nature, vol. 12(1), pages 1-13, December.
11. Elizabeth G. Fernandez & Wilson X. Mai & Kai Song & Nicholas A. Bayley & Jiyoon Kim & Henan Zhu & Marissa Pioso & Pauline Young & Cassidy L. Andrasz & Dimitri Cadet & Linda M. Liau & Gang Li & William, 2024. "Integrated molecular and functional characterization of the intrinsic apoptotic machinery identifies therapeutic vulnerabilities in glioma," Nature Communications, Nature, vol. 15(1), pages 1-18, December.
12. Cheryl A. C. Peretz & Vanessa E. Kennedy & Anushka Walia & Cyrille L. Delley & Andrew Koh & Elaine Tran & Iain C. Clark & Corey E. Hayford & Chris D’Amato & Yi Xue & Kristina M. Fontanez & Aaron A. Ma, 2024. "Multiomic single cell sequencing identifies stemlike nature of mixed phenotype acute leukemia," Nature Communications, Nature, vol. 15(1), pages 1-17, December.
13. Matteo Maria Naldini & Gabriele Casirati & Matteo Barcella & Paola Maria Vittoria Rancoita & Andrea Cosentino & Carolina Caserta & Francesca Pavesi & Erika Zonari & Giacomo Desantis & Diego Gilioli & , 2023. "Longitudinal single-cell profiling of chemotherapy response in acute myeloid leukemia," Nature Communications, Nature, vol. 14(1), pages 1-20, December.
14. Yuxuan Liu & Zhimin Gu & Hui Cao & Pranita Kaphle & Junhua Lyu & Yuannyu Zhang & Wenhuo Hu & Stephen S. Chung & Kathryn E. Dickerson & Jian Xu, 2021. "Convergence of oncogenic cooperation at single-cell and single-gene levels drives leukemic transformation," Nature Communications, Nature, vol. 12(1), pages 1-17, December.
15. Mohieddin Jafari & Mehdi Mirzaie & Jie Bao & Farnaz Barneh & Shuyu Zheng & Johanna Eriksson & Caroline A. Heckman & Jing Tang, 2022. "Bipartite network models to design combination therapies in acute myeloid leukaemia," Nature Communications, Nature, vol. 13(1), pages 1-12, December.
16. Mahmoud A. Bassal & Saumya E. Samaraweera & Kelly Lim & Brooks A. Benard & Sheree Bailey & Satinder Kaur & Paul Leo & John Toubia & Chloe Thompson-Peach & Tran Nguyen & Kyaw Ze Ya Maung & Debora A. Ca, 2022. "Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia," Nature Communications, Nature, vol. 13(1), pages 1-12, December.
17. Dohoon Lee & Bonil Koo & Seokhyeon Kim & Jamin Byun & Junshik Hong & Dong-Yeop Shin & Choong-Hyun Sun & Jaesung Kim & Ji-Joon Song & Siddhartha Jaiswal & Sung-Soo Yoon & Sun Kim & Youngil Koh, 2025. "Increased local DNA methylation disorder in AMLs with DNMT3A-destabilizing variants and its clinical implication," Nature Communications, Nature, vol. 16(1), pages 1-15, December.
18. Matteo Marchesini & Andrea Gherli & Elisa Simoncini & Lucas Moron Dalla Tor & Anna Montanaro & Natthakan Thongon & Federica Vento & Chiara Liverani & Elisa Cerretani & Anna D’Antuono & Luca Pagliaro &, 2024. "Orthogonal proteogenomic analysis identifies the druggable PA2G4-MYC axis in 3q26 AML," Nature Communications, Nature, vol. 15(1), pages 1-22, December.
19. Hanlin Wang & Guanghao Luo & Xiaobei Hu & Gaoya Xu & Tao Wang & Minmin Liu & Xiaohui Qiu & Jianan Li & Jingfeng Fu & Bo Feng & Yutong Tu & Weijuan Kan & Chang Wang & Ran Xu & Yubo Zhou & Jianmin Yang , 2023. "Targeting C/EBPα overcomes primary resistance and improves the efficacy of FLT3 inhibitors in acute myeloid leukaemia," Nature Communications, Nature, vol. 14(1), pages 1-18, December.
20. Aleksandr Ianevski & Kristen Nader & Kyriaki Driva & Wojciech Senkowski & Daria Bulanova & Lidia Moyano-Galceran & Tanja Ruokoranta & Heikki Kuusanmäki & Nemo Ikonen & Philipp Sergeev & Markus Vähä-Ko, 2024. "Single-cell transcriptomes identify patient-tailored therapies for selective co-inhibition of cancer clones," Nature Communications, Nature, vol. 15(1), pages 1-16, December.
21. Yasuo Kubota & Xiaorong Gu & Laila Terkawi & Juraj Bodo & Bartlomiej P. Przychodzen & Hussein Awada & Nakisha Williams & Carmelo Gurnari & Naomi Kawashima & Mai Aly & Arda Durmaz & Minako Mori & Ben P, 2024. "Molecular and clinical analyses of PHF6 mutant myeloid neoplasia provide their pathogenesis and therapeutic targeting," Nature Communications, Nature, vol. 15(1), pages 1-12, December.
22. Rebecca Anderson & Lance D. Miller & Scott Isom & Jeff W. Chou & Kristin M. Pladna & Nathaniel J. Schramm & Leslie R. Ellis & Dianna S. Howard & Rupali R. Bhave & Megan Manuel & Sarah Dralle & Susan L, 2022. "Phase II trial of cytarabine and mitoxantrone with devimistat in acute myeloid leukemia," Nature Communications, Nature, vol. 13(1), pages 1-13, December.
23. Tim Kong & Angelo B. A. Laranjeira & Christopher T. Letson & LaYow Yu & Shuyang Lin & Jared S. Fowles & Daniel A. C. Fisher & Sherwin Ng & Wei Yang & Fan He & Minyoung Youn & Kailen Mark & Ana San Jos, 2025. "RSK1 is an exploitable dependency in myeloproliferative neoplasms and secondary acute myeloid leukemia," Nature Communications, Nature, vol. 16(1), pages 1-20, December.
24. Jessica Ebner & Johannes Schmoellerl & Martin Piontek & Gabriele Manhart & Selina Troester & Bing Z. Carter & Heidi Neubauer & Richard Moriggl & Gergely Szakács & Johannes Zuber & Thomas Köcher & Mich, 2023. "ABCC1 and glutathione metabolism limit the efficacy of BCL-2 inhibitors in acute myeloid leukemia," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
25. Qianze Dong & Yan Xiu & Yang Wang & Christina Hodgson & Nick Borcherding & Craig Jordan & Jane Buchanan & Eric Taylor & Brett Wagner & Mariah Leidinger & Carol Holman & Dennis J. Thiele & Sean O’Brien, 2022. "HSF1 is a driver of leukemia stem cell self-renewal in acute myeloid leukemia," Nature Communications, Nature, vol. 13(1), pages 1-17, December.
26. Roger Mulet-Lazaro & Stanley Herk & Margit Nuetzel & Aniko Sijs-Szabo & Noelia Díaz & Katherine Kelly & Claudia Erpelinck-Verschueren & Lucia Schwarzfischer-Pfeilschifter & Hanna Stanewsky & Ute Acker, 2024. "Epigenetic alterations affecting hematopoietic regulatory networks as drivers of mixed myeloid/lymphoid leukemia," Nature Communications, Nature, vol. 15(1), pages 1-22, December.
27. Lina Liu & Ana Vujovic & Nandan P. Deshpande & Shashank Sathe & Govardhan Anande & He Tian Tony Chen & Joshua Xu & Mark D. Minden & Gene W. Yeo & Ashwin Unnikrishnan & Kristin J. Hope & Yu Lu, 2022. "The splicing factor RBM17 drives leukemic stem cell maintenance by evading nonsense-mediated decay of pro-leukemic factors," Nature Communications, Nature, vol. 13(1), pages 1-17, December.