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Statistical analysis of sequence-structure alignment scores

Author

Listed:
  • Brunnert, Marcus
  • Thiele, Ralf
  • Mevissen, Heinz-Theodor
  • Urfer, Wolfgang

Abstract

The structural analysis of proteins is fundamental to the analysis of protein functions. In this context, sequence-structure alignment methods are important among the different empirical methods. In order to assess the quality of sequence-structure alignments, a statistical method using a Bayesian approach proposed by Lathrop et al. (1998) will be presented. Finally, the results of a developed statistical analysis of scores of RDP(recursive dynamic programming)-sequence-structure alignments (Thiele et al., 1999) according to data of six proteins will be described.

Suggested Citation

  • Brunnert, Marcus & Thiele, Ralf & Mevissen, Heinz-Theodor & Urfer, Wolfgang, 2002. "Statistical analysis of sequence-structure alignment scores," Technical Reports 2002,38, Technische Universität Dortmund, Sonderforschungsbereich 475: Komplexitätsreduktion in multivariaten Datenstrukturen.
    • Handle: RePEc:zbw:sfb475:200238
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