IDEAS home Printed from https://ideas.repec.org/p/wop/safiwp/97-04-036.html
   My bibliography  Save this paper

Genotypes with Phenotypes: Adventures in an RNA Toy World

Author

Listed:
  • Peter Schuster

Abstract

Evolution has created the complexity of the animate world and deciphering the language of evolution is the key toward understanding nature. The dynamics of evolution is simplified by considering it as a superposition of three less sophisticated processes: population dynamics, population support dynamics, and genotype-phenotype mapping. Evolution of molecules in laboratory assays provides a sufficiently simple system for the quantitative analysis of the three phenomema. Coarse-grained notions of structures like RNA secondary structures are used as model phenotypes. They provide an excellent tool for a comprehensive analysis of the entire complex of molecular evolution. The mapping from RNA genotypes into secondary structures is highly redundant. In order to find at least one sequence for every common structure one need only search a (relatively) small part of sequence space. The existence of selectively neutral phenotypes plays an important role for the success and the efficiency of evolutionary optimization. Molecular evolution found a highly promising technological application in the design of biomolecules with predefined properties.

Suggested Citation

  • Peter Schuster, 1997. "Genotypes with Phenotypes: Adventures in an RNA Toy World," Working Papers 97-04-036, Santa Fe Institute.
    • Handle: RePEc:wop:safiwp:97-04-036
    as

    Download full text from publisher

    To our knowledge, this item is not available for download. To find whether it is available, there are three options:
    1. Check below whether another version of this item is available online.
    2. Check on the provider's web page whether it is in fact available.
    3. Perform a search for a similarly titled item that would be available.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Walter Fontana & Peter Schuster, 1997. "Shaping Space: The Possible and the Attainable in RNA Genotype-Phenotype Mapping," Working Papers 97-11-081, Santa Fe Institute.
    2. W. Fontana & P. Schuster, 1998. "Shaping Space: The Possible and the Attainable in RNA Genotype-Phenotype Mapping," Working Papers ir98004, International Institute for Applied Systems Analysis.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:wop:safiwp:97-04-036. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Thomas Krichel (email available below). General contact details of provider: https://edirc.repec.org/data/epstfus.html .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.